双相障碍早期识别的研究现状和未来思考  

Research status and future reflections on early recognition of bipolar disorder

作　　者：史家波[1] 姚志剑[1] Shi Jiabo;Yao Zhijian(Department of Psychiatry,the Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学附属脑科医院精神科,南京210029

出　　处：《中华精神科杂志》2025年第2期109-112,共4页Chinese Journal of Psychiatry

基　　金：国家自然科学基金(82271568)。

摘　　要：双相障碍多以抑郁首发、轻躁狂识别困难、常见共患躯体和精神疾病等原因,增加了诊断延迟和误诊的风险。诊断延迟和误诊导致患者难以及时得到正确治疗,从而引起疗效不佳和疾病负担加重。早期识别对于将防治关口前移和改善疾病预后至关重要。目前研究取得了一定成果,但是结果可靠性和临床转化应用不足。未来要在此方面获得突破,需要跨学科深入合作,针对特定人群开展有组织的大型前瞻性队列研究。Bipolar disorder often presents as depression,difficulty in identifying hypomania,and common comorbidities of physical and mental illnesses,increasing the risk of delayed diagnosis and misdiagnosis.Delayed diagnosis and misdiagnosis make it difficult for patients to receive timely and correct treatment,resulting in poor efficacy and increased disease burden.Therefore,early recognition is crucial for moving the prevention and treatment checkpoint forward and improving disease prognosis.At present,research has achieved certain results,but the reliability and clinical application of the results are insufficient.In the future,breakthroughs in this area will require in-depth interdisciplinary collaboration and organized large-scale prospective cohorts targeting specific populations.

关 键 词：双相情感障碍 早期识别 高危人群 

分 类 号：R749[医药卫生—神经病学与精神病学]