食管良性狭窄的内镜下治疗进展  

Progress in endoscopic treatment of benign esophageal stenosis

作　　者：黄甜甜 王翀[1] HUANG Tiantian;WANG Chong(Department of Gastroenterology,the First Affiliated Hospital of Nanchang University,Jiangxi Provincial Key Laboratory of Digestive Diseases,Jiangxi Clinical Research Center for Gastroenterology,Nanchang 330006,Jiangxi,China)

机构地区：[1]南昌大学第一附属医院消化内科,消化疾病江西省重点实验室,江西省消化系统疾病临床研究中心,江西南昌330006

出　　处：《实用医学杂志》2025年第4期465-470,共6页The Journal of Practical Medicine

基　　金：国家自然科学基金项目(编号:82260113);江西省自然科学基金项目(编号:20212BAB206025);江西省卫生健康委科技计划(编号:202130326)。

摘　　要：食管狭窄主要是指食道本身的疾病或者是并发症引起的食道管腔的狭窄,分为良性狭窄和恶性狭窄,食管良性狭窄可由先天性食管狭窄导致,也可继发于食管癌术后、食管炎等各种疾病,其引起的症状如吞咽困难,对患者的生活造成了不同程度的影响,并给社会带来了巨大的经济和医疗负担,如何有效防治食管良性狭窄已成为当前亟待解决的医学难题。目前,随着内镜技术的不断发展、成熟,内镜下扩张治疗、内镜下切开术、内镜下支架置入术、再生医学等应用于食管良性狭窄的治疗,并取得了一定疗效。现今,再生医学获得越来越广泛的关注,其主要是通过在结构和功能上重建正常组织,促进早期再上皮化发挥作用,可应用于食管良性狭窄的防治。然而,食管良性狭窄治疗方法如何选择,除考虑患者病情外,还需考虑治疗效果、并发症、复发率等问题,基于此,该文就目前食管良性狭窄的内镜治疗进展进行了综述,旨在为食管良性狭窄的临床治疗提供思路。Esophageal stenosis primarily refers to the narrowing of the esophageal lumen caused by intrinsic esophageal diseases or their complications,categorized into benign and malignant types.Benign esophageal stenosis can arise from congenital factors or secondary conditions such as postoperative changes following esophageal cancer surgery,esophagitis,and other inflammatory processes.This condition is characterized by dysphagia,significantly impacting patients′quality of life and imposing substantial economic and medical burdens on society.Effective prevention and management of benign esophageal stenosis have emerged as an urgent medical challenge.With advancements in endoscopic techniques,various interventions including endoscopic dilation,endoscopic mucosal resection,endoscopic stenting,and regenerative medicine have been applied to treat benign esophageal stenosis,achieving promising therapeutic outcomes.In recent years,regenerative medicine has gained prominence,promoting early re⁃epithelialization through the structural and functional reconstruction of normal tissues,offering potential applications in the prevention and treatment of benign esophageal stenosis.However,selecting an appropriate treatment method for benign esophageal stenosis requires a comprehensive evaluation of the patient′s condition,therapeutic efficacy,potential complications,recurrence rates,and other relevant factors.This review aims to summarize the current progress in endoscopic treatments for benign esophageal stenosis,providing valuable insights for clinical practice.

关 键 词：食管良性狭窄 内镜下切开术 内镜下扩张治疗 再生医学 

分 类 号：R571.1[医药卫生—消化系统]