氢氧化钙联合氯己定根管消毒治疗对牙髓炎患者血清炎症因子的影响  

Effect of Calcium Hydroxide Combined with Chlorhexidine Root Canal Disinfection on Serum Inflammatory Factors in Patients with Pulpitis

作　　者：李露平 LI Luping(Department of Stomatology,Fuzhou Maternal and Child Health Hospital,Fuzhou 344000,China)

机构地区：[1]抚州市妇幼保健院(抚州市第二人民医院)口腔科,江西抚州344000

出　　处：《中国医学创新》2025年第5期103-107,共5页Medical Innovation of China

摘　　要：目的:探讨氢氧化钙联合氯己定根管消毒治疗对牙髓炎患者血清炎症因子的影响。方法:选择2021年6月-2023年6月抚州市妇幼保健院收治的牙髓炎患者76例,以随机数字表法分为两组。两组均行根管治疗,对照组38例在根管处用氢氧化钙,研究组38例在根管处用氢氧化钙联合氯己定。比较两组治疗效果、牙周指数、疼痛情况、炎症因子及并发症。结果:研究组总有效率高于对照组,并发症发生率低于对照组,差异均有统计学意义(P<0.05)。两组治疗1个月后菌斑指数、出血指数、探诊深度、牙龈指数、炎症因子,以及治疗1、2、3 d疼痛评分均降低,且研究组均低于对照组,差异均有统计学意义(P<0.05)。结论:牙髓炎患者采用氢氧化钙联合氯己定根管消毒治疗效果优于单用氢氧化钙,更利于改善患者牙周指数,抑制炎症反应,减轻疼痛情况,且并发症较少。Objective:To investigate the effect of Calcium Hydroxide combined with Chlorhexidine root canal disinfection on serum inflammatory factors in patients with pulpitis.Method:A total of 76 patients with pulpitis treated in Fuzhou Maternal and Child Health Hospital from June 2021 to June 2023 were selected and divided into two groups by random number table method.Both groups were treated with root canal therapy.38 cases in the control group were treated with Calcium Hydroxide at the root canal,while 38 cases in the study group were treated with Calcium Hydroxide combined with Chlorhexidine at the root canal.The treatment effect,periodontal index,pain,inflammatory factors and complications were compared between the two groups.Result:The total effect rate of the study group was higher than that of the control group,and the complication rate was lower than that of the control group,the differences were statistically significant(P<0.05).The plaque index,bleeding index,probing depth,gingival index,inflammatory factors after 1 month of treatment,and pain scores at 1,2 and 3 d of treatment in the two groups were decreased,and those in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The effect of Calcium Hydroxide combined with Chlorhexidine root canal disinfection in patients with pulpitis is better than that of Calcium Hydroxide alone,which is more conducive to improve the periodontal index,inhibit inflammatory reaction,reduce pain,and has fewer complications.

关 键 词：牙髓炎 根管治疗 氢氧化钙 氯己定 炎症因子 

分 类 号：R781.31[医药卫生—口腔医学]