改良电休克治疗超高龄难治性抑郁症患者1例  

Super-elderly treatment resistant depression patient treated with modified electroconvulsive therapy:a case report

作　　者：崇杉 熊娜娜 范滕滕 Chong Shan;Xiong Nana;Fan Tengteng(Peking University Sixth Hospital,Peking University Institute of Mental Health,National Health Commission Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Six Hospital),Beijing 100191,China)

机构地区：[1]北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100191

出　　处：《四川精神卫生》2025年第1期84-88,共5页Sichuan Mental Health

基　　金：国家重点研发计划项目(项目名称:脑深部电刺激治疗抑郁症安全性和有效性的动物研究,项目编号:2019YFC0118502)。

摘　　要：本文报道1例超高龄难治性抑郁症患者接受改良电休克治疗(MECT)。患者女性,87岁,抑郁症病史8年,病程呈间断性发作,既往对多种抗抑郁药物反应不佳,接受MECT后抑郁症状缓解。近两年,患者经历生活应激事件后抑郁症复发,接受MECT后好转,然而停止MECT后抑郁症多次复燃,故再入院继续接受MECT以延续治疗获益,患者对MECT整体耐受性尚可。结合国内外研究,本文对超高龄难治性抑郁症患者的治疗选择进行探讨,以期为MECT在超高龄抑郁症患者中的应用提供参考。The paper reported a case of super-elderly patient with treatment-resistant depression who underwent modified electroconvulsive therapy(MECT).The patient was an 87-year-old female presented to the hospital with an 8-year history of depressive disorder marked by intermittent episodes,who exhibited poor response to various antidepressants while achieved a significant improvement after receiving MECT.In the past two years,the patient experienced a recurrence of depression following life stress events.The condition showed improvement with the administration of MECT.However,after discontinuation of MECT,the depression relapsed multiple times,prompting rehospitalization for continued MECT to sustain clinical benefits.The patient demonstrated overall tolerable adherence to MECT.Based on research of domestic and international,this paper explored treatment options for super-elderly patients with treatment-resistant depression,aiming to provide insights into the application of MECT in the management of depression among super-elderly patients with depression.[Funded by National Key Research and Development Project(number,2019YFC0118502)]

关 键 词：改良电休克治疗 超高龄 难治性抑郁症 维持治疗 

分 类 号：R749.4[医药卫生—神经病学与精神病学]