Follow-up of elderly gastric cancer post-radical surgery: Trauma, complications, and prognosis  

作　　者：Li-Ling Zhu Rui-Zhi Shen 

机构地区：[1]Department of Geriatrics,Jiangnan University Medical Center,Wuxi 214001,Jiangsu Province,China [2]Department of Oncology,Jiangnan University Medical Center,Wuxi 214001,Jiangsu Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2025年第3期331-337,共7页世界胃肠外科杂志(英文)

摘　　要：BACKGROUND The incidence of gastric cancer in the elderly is increasing;however,standardized surgical approaches are lacking.AIM To investigate the effects of radical surgery on the trauma response,postoperative complications,and long-term prognosis in elderly patients with gastric cancer.METHODS Between January 2020 and December 2023,110 gastric cancer patients admitted to the Department of Oncology Jiangnan University Medical Center were cate-gorized into a control group(40 cases)and an observation group(70 cases)based on surgical method differences.The control and observation group received palli-ative surgery and radical surgery,respectively,and were further divided into open(25 cases)and laparoscopic(45 cases)surgery.Surgical outcomes,trauma indicators,complication rates,and long-term survival at 6 months,1-,and 2-years were compared.RESULTS Laparoscopic surgery showed superior surgical outcomes compared to the open surgery and control groups(P<0.05).Trauma indicators were lowest in the lapa-roscopic group and highest in the control group(P<0.05).No significant difference was observed in the complication rates between the open and laparo-scopic groups(P>0.05),but both were higher than those in the control group(P<0.05).No significant differences were found in survival rates at different follow-up periods between the laparoscopic and open groups(P>0.05);however,both groups showed higher survival rates than the control group(P<0.05).CONCLUSION Radical surgery in elderly patients with gastric cancer reduces surgical trauma response,facilitates postoperative recovery,and improves long-term survival rates,albeit with an increased risk of complications.Laparoscopic radical surgery further minimizes postoperative trauma,with no significant difference in complication rates and survival prognosis compared with open radical surgery.

关 键 词：Radical surgery Elderly gastric cancer Trauma stress response COMPLICATIONS Long-term prognosis 

分 类 号：R735.2[医药卫生—肿瘤]