基于行为转变理论的护理干预对卵巢癌患者化疗期间的治疗依从性及细胞毒性反应的影响  

Effect of Nursing Intervention Based on Behavioral Change Theory on Treatment Compliance and Cytotoxic Reaction of Ovarian Cancer Patients During Chemotherapy

作　　者：沈东梅 SHEN Dongmei(Department of Gynecology,Xiamen University Affiliated Women and Children’s Hospital,Xiamen,Fujian 361003,China)

机构地区：[1]厦门大学附属妇女儿童医院妇科,福建厦门361003

出　　处：《中国医药指南》2025年第5期168-171,共4页Guide of China Medicine

摘　　要：目的分析基于行为转变理论的护理干预对卵巢癌患者化疗期间治疗依从性及细胞毒性反应的影响。方法选取厦门大学附属妇女儿童医院2023年1月—12月接受化疗的280例卵巢癌患者,将其按照随机数字表法分成对照组(n=140)与研究组(n=140)。分别接受常规护理干预、基于行为转变理论的护理干预,对两组的治疗依从性、心理状态(SAS、SDS评分)、癌性疲乏、自我效能感、细胞毒性反应进行分析比较。结果相比于对照组81.43%(114/140),研究组的治疗依从率更高,为96.43%(135/140)(P<0.05)。干预后,两组的SDS评分、SAS评分均较干预前降低,且与对照组比较,研究组的SDS评分、SAS评分均更低(P<0.05)。干预后,两组情感疲乏、躯体疲乏、认知疲乏评分均降低,且与对照组比较,研究组的情感疲乏、躯体疲乏、认知疲乏评分均更低(P<0.05)。干预后,两组自我减压、自我决策、正性态度评分均升高,且与对照组比较,研究组的自我减压、自我决策、正性态度评分均更高(P<0.05)。与对照组相比较,研究组的脱发、消化道反应、周围神经炎、骨髓抑制的发生率均更低,差异有统计学意义(P<0.05)。结论为卵巢癌患者提供基于行为转变理论的护理干预,不仅能提升其治疗依从性,改善其癌因性疲乏程度,减轻不良情绪,而且能有效提升自我效能感,减轻化疗细胞毒性反应。Objective To analyze the effect of nursing intervention based on behavior change theory on treatment compliance and cytotoxic reaction of ovarian cancer patients during chemotherapy.Methods A total of 280 ovarian cancer patients who received chemotherapy at the Women and Children’s Hospital Affiliated to Xiamen University from January to December 2023 were selected and divided into a control group(n=140)and a study group(n=140)according to the random number table method.The two groups respectively received routine nursing interventions and nursing interventions based on the theory of behavior change.The treatment compliance,psychological state(SAS and SDS scores),cancer-related fatigue,self-efficacy,and cytotoxic reactions of the two groups were analyzed and compared.Results Compared with the control group at 81.43%(114/140),the treatment compliance rate of the study group was higher,at 96.43%(135/140)(P<0.05).After the intervention,the SDS and SAS scores of both groups decreased compared with before the intervention,and the SDS and SAS scores of the study group were both lower than those of the control group(P<0.05).After the intervention,the scores of emotional fatigue,physical fatigue,and cognitive fatigue in both groups decreased,and the scores of emotional fatigue,physical fatigue,and cognitive fatigue in the study group were all lower than those in the control group(P<0.05).After the intervention,the scores of self-relaxation,self-decision-making,and positive attitude in both groups increased,and the scores of self-relaxation,self-decision-making,and positive attitude in the study group were all higher than those in the control group(P<0.05).Compared with the control group,the incidence of hair loss,gastrointestinal reactions,peripheral neuritis,and bone marrow suppression in the study group was all lower,with statistical significance(P<0.05).Conclusions Providing nursing intervention based on behavior change theory for ovarian cancer patients can not only improve their treatment compliance,improve the de

关 键 词：卵巢癌 行为转变理论 护理干预 化疗 治疗依从性 细胞毒性反应 

分 类 号：R737.31[医药卫生—肿瘤] R473.73[医药卫生—临床医学]