基于肠道菌群学说探讨“肾为胃之关”在慢传输型便秘治疗中的理论内容  

Theoretical Connotation of“Kidney Serving as the Gateway to Stomach”in the Treatment of Slow Transit Constipation Based on Intestinal Flora

作　　者：胡露楠 何友成 刘启鸿[1,2,3] 柯晓 任彦[1,2,3] HU Lunan;HE Youcheng;LIU Qihong;KE Xiao;REN Yan(The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine,Fuzhou 350003,China;Fujian Clinical Medical Research Centre of Chinese Medicine for Spleen and Stomach,Fuzhou 350003,China;Fujian Famous Chinese Medicine Practitioner KE Xiao Studio,Fuzhou 350003,China;Longhua Hospital/Institute of Spleen and Stomach Diseases,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]福建中医药大学附属第二人民医院,福州350003 [2]福建省中医脾胃临床医学研究中心,福州350003 [3]福建省名中医柯晓工作室,福建350003 [4]上海中医药大学附属龙华医院/脾胃病研究所,上海200032

出　　处：《世界中医药》2024年第23期3664-3668,共5页World Chinese Medicine

基　　金：国家自然科学基金面上项目(82274282);中央引导地方科技发展资金项目(2023L3013);福建省中医脾胃临床医学研究中心(2021Y2010);柯晓福建省名中医工作室建设项目(闽卫中医[2022]112号)。

摘　　要：慢传输型便秘(STC)是临床常见的功能性便秘的类型之一,近年来,越来越多的研究发现肠道菌群可以介导STC的发生发展,且脾肾两脏的生理病理密切相关。立足肠道菌群,围绕“肾为胃之关”的理论内涵,深入探讨其在STC治疗中的具体运用,认为肠道菌群是阐释中医药治疗STC的重要途径。“治脾(胃),应以气机为先,气血为本”“治肾应以精气为根,阴阳为本”,是中医药治疗STC的重要理念。基于肠道菌群进一步发挥“肾为胃之关”理论的指导作用,对STC的临床辨治大有裨益。Slow transit constipation(STC)is a common subtype of functional constipation in clinical practice.Recent studies have shown that the intestinal flora plays a critical role in the development of STC,and that the physiological and pathological relationships between the spleen and kidneys are closely connected.Based on the theory of“kidney serving as the gateway to stomach”,this article explores the specific application of intestinal flora in the treatment of STC,arguing that intestinal flora serves as a crucial pathway to understanding the effectiveness of traditional Chinese medicine(TCM)in treating STC.The key TCM principles in treating STC include that“when treating the spleen(stomach),the focus should be on regulating the qi movement and nourishing qi and blood”,and“when treating the kidneys,the essence and qi should be the foundation,with balance between yin and yang as the core”.The application of intestinal flora in conjunction with the theory of“kidney serving as the gateway to stomach”is highly beneficial in clinical differentiation and treatment of STC,providing significant insights for improving the efficacy of TCM in addressing this condition.

关 键 词：慢传输型便秘 肠道菌群 肾为胃之关 中医药 理脾(胃)调肾法 理论内容 功能性便秘 肠道微生态系统 

分 类 号：R574.62[医药卫生—消化系统]