快速细胞学评估在乳腺包块诊断中的应用  

Application of rapid on-site cytological evaluation in the diagnosis of breast masses

作　　者：米会敏 蔡媛[1] MI Huimin;CAI Yuan(Department of Pathology,Baoji Central Hospital,Baoji Shaanxi 721300,China)

机构地区：[1]宝鸡市中心医院病理科,陕西宝鸡721300

出　　处：《临床与病理杂志》2024年第10期1398-1402,共5页Journal of Clinical and Pathological Research

基　　金：宝鸡市卫生健康委员会课题(2021-029)。

摘　　要：目的:乳腺包块是女性常见的临床症状,本文探讨快速现场细胞学评估(rapid on-site cytological assessment,ROSE)在乳腺包块中的诊断作用。方法:收集宝鸡市中心医院乳腺包块病例597例,乳腺包块术前影像学分类(thyroid imaging reporting and date system,TI-RADS)均为4级或4级以上,穿刺后均进行ROSE,并将其诊断结果(敏感度、特异度、假阳性率、假阴性率等)与组织石蜡切片的诊断结果进行比较。结果:乳腺包块患者597例,其中男6例,女591例。与组织石蜡切片相比,快速细胞学印片敏感度为93.72%、特异度为99.03%、假阳性率为0.97%、假阴性率为6.27%。结论:ROSE与石蜡切片的病理学诊断有同样的意义,可极大地提高乳腺科日间的手术率,适合推广。Objective:Breast masses are common clinical symptoms in women.This study explores the diagnostic and therapeutic role of rapid on-site cytological evaluation(ROSE)in breast masses.Methods:A total of 597 cases of breast masses from Baoji Central Hospital were collected.All preoperative imaging classifications by thyroid imaging reporting and data system(TI-RADS)were level 4 or above.ROSE was performed after aspiration,and its diagnostic sensitivity,specificity,false-positive rate,and false-negative rate were compared with the results of tissue paraffin section pathology.Results:Among the 597 breast mass cases,6 were male and 591 were female.Compared to tissue paraffin sections,the sensitivity of rapid cytology smears was 93.72%,specificity was 99.03%,false-positive rate was 0.97%,and false-negative rate was 6.27%.Conclusion:ROSE provides the same diagnostic significance as paraffin section pathology and can greatly improve the day surgery rate in breast surgery.It is suitable for wider application.

关 键 词：快速印片细胞学 组织石蜡切片 乳腺包块 病理学诊断 日间手术 

分 类 号：R73[医药卫生—肿瘤]