水杨酸分子印迹聚合物整体柱合成及其固相微萃取应用  

Monolithic Synthesis of Salicylic Acid Molecularly Imprinted Polymers and the Application in Solid Phase Micro-extraction

作　　者：王岩[1] WANG Yan(Guangxi Modern Polytechnic College,Hechi Guangxi 547000,China)

机构地区：[1]广西现代职业技术学院,广西河池547000

出　　处：《化肥设计》2025年第1期36-39,共4页Chemical Fertilizer Design

基　　金：2021年广西高校中青年教师基础能力提升项目“水杨酸分子印迹聚合物的理论设计与制备”(2021KY1424);广西有色金属产业科技成果转化中试研究基地。

摘　　要：以水杨酸为模板、4-乙烯吡啶为单体,通过原位聚合(遵循模板分子∶功能单体∶交联剂=1∶4∶18)合成新型高分子材料,并用于色谱柱填充,实现高效固相微萃取。经细致优化萃取参数,构建了高效液相微萃取联用技术,该技术检测下限为1.2 ng/mL,回收率为92.1%~105.8%,操作简便,选择性高。实验证明:本法灵敏度高,适用于环境样品中水杨酸测定,为相关研究与监测提供有力支持。通过精确调控溶液体积、pH值、去垢剂种类与用量及萃取速度,确保了技术的准确性和可靠性。Using salicylic acid as the template and 4-vinylpyridine as the monomer,a novel polymer material is synthesized via in-situ polymerization(following template molecule∶functional monomer∶cross-linker=1∶4∶18)and is used for chromatographic column filling to achieve high efficiency solid phase micro-extraction.After careful optimization of extraction parameters,high performance liquid phase micro-extraction combination technology has been established.With the detection limit of 1.2 ng/mL and the recovery rate of 92.1%~105.8%,the operation of this technology is simple and highly selective.Experimental results show that the method is sensitive and suitable for measuring salicylic acid in environmental samples,which provides strong support for related research and monitoring.The accuracy and reliability of the technology are ensured by precisely adjusting the volume of solution,the pH value,the type and dosage of detergent as well as the extraction speed.

关 键 词：水杨酸 固相微萃取 环境水 

分 类 号：TQ316.31[化学工程—高聚物工业]