中国恶性肿瘤整合诊治指南-肛管癌(2024版)  

CACA guidelines for holistic integrative management of anal cancer(2024 Edition)

作　　者：中国抗癌协会 中国抗癌协会大肠癌专业委员会 樊代明 王锡山[3] 顾晋 丁克峰[5] 房学东[6] 沈琳 徐忠法 许剑民[8] 王贵玉 王贵英 顾艳宏[11] 金晶[12] 刘骞[3] 谢玲女[13] Anti-Cancer Association China;the Committee of Colorectal Cancer CACA

机构地区：[1]不详 [2]空军军医大学西京消化病医院 [3]中国医学科学院肿瘤医院 [4]北京大学肿瘤医院 [5]浙江大学医学院附属第二医院 [6]吉林大学中日联谊医院 [7]山东第一医科大学第三附属医院 [8]复旦大学附属中山医院 [9]哈尔滨医科大学附属第二医院 [10]河北医科大学第二医院 [11]江苏省人民医院 [12]中国医学科学院肿瘤医院深圳医院 [13]浙江省肿瘤医院

出　　处：《中华结直肠疾病电子杂志》2024年第6期441-449,共9页Chinese Journal of Colorectal Diseases(Electronic Edition)

摘　　要：《中国恶性肿瘤整合诊治指南-肛管癌(2024版)》充分参考了国内外最新研究成果,广泛整合相关领域专家意见,形成了更新版本。相较于上一版,诊断流程图中加入HPV检测;在内科治疗中,无活动性自身免疫性疾病患者可考虑帕博利珠单抗和纳武利尤单抗作为复发或转移性肛管鳞状细胞癌的二线治疗方案;转移性疾病诊疗流程图中增加免疫治疗;中医药治疗部分调整“辨证施治方法”为“辨病论治与辨证施治相结合”,并明确其在围术期、化疗期、放疗期及随诊期和姑息治疗中的临床价值;病理学诊断部分将“浸润性癌活检可能误诊为高级别上皮内瘤变或黏膜内癌”修改为“浸润性癌活检可能诊断为高级别上皮内瘤变”;在造口管理部分增加对患者的心理评估。CACA guidelines for holistic integrative management of anal cancer(2024 Edition)fully refers to the latest researches at home and abroad,integrates experts’opinions in relevant fields and forms an updated version.Compared to the previous edition,the diagnostic flowchart now includes HPV testing.In internal medicine treatment,patients without active autoimmune diseases may consider pembrolizumab and nivolumab as second-line therapies for recurrent or metastatic anal squamous cell carcinoma.Immune therapy has been added to the treatment flowchart for metastatic diseases.In the traditional Chinese medicine section,the phrase“clinical diagnosis and treatment should be offered based on syndrome differentiation”has been adjusted to“adopting the combination of treatment based on disease differentiation and treatment based on syndrome differentiation”,with the clinical value of traditional Chinese medicine treatment in perioperative,chemotherapy,radiotherapy,follow-up,and palliative treatment periods newly added.In the pathology diagnosis section,the phrase“invasive carcinoma may be misdiagnosed as high-grade intraepithelial neoplasia or intramucosal carcinoma”has been revised to“invasive carcinoma may be diagnosed as highgrade intraepithelial neoplasia”.Additionally,psychological assessment for patients has been added to the stoma management section.

关 键 词：肛管 指南 外科治疗 内科治疗 放疗 中医药治疗 

分 类 号：R73[医药卫生—肿瘤]