经中间入路与侧方入路腹腔镜手术治疗结直肠癌患者的临床效果分析  

Analysis of the Clinical Efficacy of Laparoscopic Surgery via Medial Approach and Lateral Approach in the Treatment of Colorectal Cancer Patients

作　　者：张华 ZHANG Hua(Department of Gastrointestinal Abdominal Wall Hernia Surgery,Jinxiang County People's Hospital,Jining272200,China)

机构地区：[1]金乡县人民医院胃肠腹壁疝外科,山东济宁272200

出　　处：《反射疗法与康复医学》2024年第24期117-120,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨经中间入路与侧方入路腹腔镜手术治疗结直肠癌患者的临床效果。方法选取2020年1月—2023年10月金乡县人民医院收治的82例结直肠癌患者为研究对象,按随机数字表法将其分为对照组和观察组,各41例。对照组行侧方入路腹腔镜手术治疗,观察组行经中间入路腹腔镜手术治疗。比较两组的手术情况、术后胃肠功能恢复情况、肿瘤标志物水平、生活质量及并发症发生情况。结果观察组手术时间、住院时间分别为(120.41±12.34)min、(10.05±1.23)d,均短于对照组的(143.55±13.41)min、(12.84±1.27)d,淋巴结清扫数目为(22.41±2.37)个,多于对照组的(19.02±1.53)个,术中出血量为(52.41±5.23)mL,少于对照组的(68.96±5.84)mL,组间差异有统计学意义(P<0.05)。观察组肛门排气时间、肠鸣音恢复时间、排便时间及进食时间均短于对照组,组间差异有统计学意义(P<0.05)。术后1个月,观察组糖类抗原199、癌胚抗原、糖类抗原125水平均低于对照组,组间差异有统计学意义(P<0.05);观察组世界卫生组织生存质量测定量表简表中各个领域评分均高于对照组,组间差异有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。结论相较经侧方入路腹腔镜手术,经中间入路腹腔镜手术治疗结直肠癌效果更佳,可减轻手术创伤,加快术后胃肠功能恢复,降低肿瘤标志物水平,且安全可靠。Objective To investigate the clinical effect of laparoscopic treatment of colorectal cancer patients via the middle approach and lateral approach.Methods A total of 82 patients with colorectal cancer treated in Jinxiang County People's Hospital from January 2020 to October 2023 were selected as the research objects and divided into a control group and an observation group according to random number table method,with 41 cases in each group.The control group underwent lateral approach laparoscopic surgery,and the observation group underwent middle approach laparoscopic surgery.Operation,gastrointestinal function recovery,tumor marker level,quality of life and occurrence of complications were compared between the two groups.Results The surgical time and hospitalization time of the observation group were(120.41±12.34)min and(10.05±1.23)d,respectively,which were shorter than(143.55±13.41)min and(12.84±1.27)d of the control group,the number of lymph node dissections was(22.41±2.37),which was higher than(19.02±1.53)of the control group,the intraoperative blood output was(52.41±5.23)mL,which was less than(68.96±5.84)mL of the control group,and the differences between the groups were statistically significant(P<0.05).The observation group had shorter anal exhaust time,bowel sound recovery time,defecation time,and feeding time than those in the control group,and the differences between the groups were statistically significant(P<0.05).One month after surgery,the levels of carbohydrate antigen 199,carcinoembryonic antigen,and carbohydrate antigen 125 in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05);the scores in various fields of the World Health Organization Quality of Life-Brief Version in the observation group were higher than those in the control group,the differences between the groups were statistically significant(P<0.05).There was no statistically significant difference in the incidence of complications between t

关 键 词：结直肠癌 腹腔镜手术 胃肠功能 肿瘤标志物 

分 类 号：R735[医药卫生—肿瘤]