原发性腹膜后肉瘤联合消化道切除及重建的研究现状及进展  

Research status and progress of primary retroperitoneal sarcomas combined resection and reconstruction of digestive tract

作　　者：彭帅 陈勇 曲兴龙[1] 张洪强 王炳 屈国伦 王洪波 王康伟 PENG Shuai;CHEN Yong;QU Xinglong;ZHANG Hongqiang;WANG Bing;QU Guolun;WANG Hongbo;WANG Kangwei(Department of Surgical Oncology,Minhang Branch,Shanghai Cancer Center,Fudan University,Shanghai 200240,China;Department of Musculoskeletal Surgery,Shanghai Cancer Center,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属肿瘤医院闵行分院肿瘤外科,上海200240 [2]复旦大学附属肿瘤医院骨软组织外科,上海200032

出　　处：《肿瘤》2024年第10期1069-1076,共8页Tumor

摘　　要：原发性腹膜后肉瘤由于其特殊的解剖结构,早期缺乏特异性的临床表现,而导致诊断延迟。当患者出现明显症状或临床检查触及包块时,肿瘤体积多已显著增大,且多呈侵袭性生长,常累及毗邻脏器。外科手术治疗时常需要联合多脏器整块切除,其中消化道器官的联合切除与功能性重建已成为重要的手术组成部分。原发性腹膜后肉瘤的手术具有切除范围广、操作难度高的特点,难以在广泛清晰的阴性切缘下彻底切除,且易局部复发,这些都显著增加了患者手术治疗的复杂性。目前,关于原发性腹膜后肉瘤的外科手术治疗研究,尤其是涉及联合消化道切除与功能性重建的系统性研究仍显不足。为深化临床认知、优化手术策略,本文通过系统回顾国内外相关文献的方式,对原发性腹膜后肉瘤联合消化道切除与功能性重建的研究现状及最新进展进行综述。Primary retroperitoneal sarcomas,due to its special anatomical structure and lack of specific clinical manifestations in early stages,often leads to delayed diagnosis.because of the lack of specific clinical manifestations.By the time patients present with noticeable symptoms or palpable masses during clinical examination,the tumors has typically grown significantly in size and exhibits invasive growth patterns,frequently involving adjacent organs.Surgical treatment often necessitates multivisceral en bloc resection,with combined resection and functional reconstruction of gastrointestinal organs becoming critical components of the procedure.The surgical management of primary retroperitoneal sarcoma is characterized by extensive resection scope,technical complexity,and challenges in achieving complete tumor removal with wide clear negative margins.Additionally,the high propensity for local recurrence further increases the complexity of patient management.Current research on surgical treatment strategies for primary retroperitoneal sarcoma,particularly systematic studies focusing on combined gastrointestinal resection and functional reconstruction,remains insufficient.To enhance clinical understanding and optimize surgical approaches,this article systematically reviews domestic and international literature to summarize current research status and recent advancements in combined gastrointestinal resection and functional reconstruction for primary retroperitoneal sarcoma.

关 键 词：腹膜后肉瘤 联合切除 消化道切除及重建 

分 类 号：R735.4[医药卫生—肿瘤]