纤维肌痛综合征合并偏头痛患者的临床特征  

Clinical characteristics of patients with interstitial cystitis/bladder pain syndrome accompanied by migraine

作　　者：傅增辉 金艳 林再红 FU Zenghui;JIN Yan;LIN Zaihong(Department of Neurology,the Third Affiliated Hospital of Qiqihar Medical University,Qiqihar 161002,Heilongjiang,China)

机构地区：[1]齐齐哈尔医学院附属第三医院神经内科,黑龙江齐齐哈尔161002

出　　处：《暨南大学学报(自然科学与医学版)》2025年第1期37-42,81,共7页Journal of Jinan University(Natural Science & Medicine Edition)

基　　金：黑龙江省卫生健康委员会科研项目(20220303070603)。

摘　　要：目的:探讨纤维肌痛综合征(fibromyalgia syndrome,FMS)合并偏头痛的临床特征。方法:研究纳入2021年01月至2023年12月齐齐哈尔医学院附属第三医院收治的210例FMS患者,收集其一般资料和临床资料,采用广泛疼痛指数(widespread pain index,WPI),症状严重程度(symptom severity scale,SSS),纤维肌痛严重程度(fibromyalgia severity,FS),疼痛、焦虑、睡眠和躯体化症状评分等量表对其进行评估。结果:210例FMS患者中合并偏头痛的患者有108例(51.43%)。与无偏头痛的FMS患者相比,合并偏头痛的患者FMS病程较长(P=0.001),其WPI评分(P=0.003)、SSS评分(P=0.001)、FS评分(P=0.002)、疼痛评分(P=0.008)、焦虑评分(P=0.005)、睡眠评分(P=0.004)和躯体化症状评分(P=0.009)均较高。合并偏头痛的FMS患者的FS评分与头痛病程(P=0.013)、头痛发作频率(P=0.019)、头痛持续时间(P=0.037)、FMS病程(P=0.025)、疼痛评分(P=0.028)、焦虑评分(P=0.030)、睡眠评分(P=0.035)和躯体化症状评分(P=0.008)呈正相关。结论:偏头痛的存在会加重FMS的临床症状,FMS合并偏头痛时FMS症状与头痛症状、焦虑、睡眠障碍具有关联性。Objective:To investigate the clinical characteristics of fibromyalgia syndrome(FMS)complicated by migraine.Methods:The study included 210 FMS patients who were treated at the Third Affiliated Hospital of Qiqihar Medical University from January 2021 to December 2023.General and clinical data were collected.Assessment was conducted using scales such as the wide spread pain index(WPI),symptom severity scale(SSS),fibromyalgia severity(FS),pain score,anxiety score,sleep score,and somatic symptom score.Results:Among the 210 FMS patients,108(51.43%)had concomitant migraine.Compared with FMS patients without migraine,those with migraine had significantly higher scores in FMS duration(P=0.001),WPI score(P=0.003),SSS score(P=0.001),FS score(P=0.002),pain score(P=0.008),anxiety score(P=0.005),sleep score(P=0.004),and somatization symptom score(P=0.009).In FMS patients with migraine,FS scores were positively correlated with headache duration(P=0.013),headache frequency(P=0.019),headache duration(P=0.037),FMS duration(P=0.025),pain score(P=0.028),anxiety score(P=0.030),sleep score(P=0.035),and somatization symptom score(P=0.008).Conclusion:The presence of migraine exacerbates the clinical symptoms of FMS,and there is a correlation between FMS symptoms and headache symptoms,anxiety,and sleep disturbances when FMS is complicated by migraine.

关 键 词：纤维肌痛综合征 偏头痛 焦虑 睡眠障碍 

分 类 号：R747.9[医药卫生—神经病学与精神病学]