体外循环心脏手术后乳酸升高的影响因素及其不良健康结局的研究进展  

Factors Influencing Lactic Acid Elevation and Adverse Health Outcomes After Cardiopulmonary Bypass

作　　者：刘华雪 刘雪贞 谭赛赛 郭春梅 储华敏 LIU Huaxue;LIU Xuezhen;TAN Saisai;GUO Chunmei;CHU Huamin(Department of Cardiac Surgery,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250013,Shandong,China;Chronic Non-communicable Disease Prevention and Control Section,Taian Center for Disease Control and Prevention,Taian 271021,Shandong,China)

机构地区：[1]山东第一医科大学附属省立医院心外科,山东济南250013 [2]泰安市疾病预防控制中心慢性非传染性疾病防治科,山东泰安271021

出　　处：《心血管病学进展》2025年第2期118-123,共6页Advances in Cardiovascular Diseases

摘　　要：高乳酸血症是体外循环心脏手术后常见的并发症,其发生与术中低灌注、组织缺氧、炎症反应、代谢紊乱、体外循环时间长等多种因素有关。现旨在系统地总结和分析体外循环心脏手术后乳酸升高的原因及其对患者健康结局的影响,以此为基础,探讨可行的临床干预策略,为心脏手术后乳酸升高患者的管理提供更加合理的参考和指南,并对心脏手术后的风险评估和临床干预策略的制定产生积极的推动作用。Hyperlactacidemia is a common complication after cardiopulmonary bypass surgery.Its occurrence is related to many factors,such as tissue hypoxia,inflammatory response and metabolic disorders,intraoperative hypoperfusion.This paper aims to systematically summarize and analyze the causes of elevated lactic acid after cardiopulmonary bypass surgery and its impact on patient health outcomes,and on this basis,explore feasible clinical intervention strategies,aiming to provide a more reasonable reference and guideline for the management of patients in the later stage of cardiac surgery,and positively promote risk assessment and the development of clinical intervention strategies after cardiac surgery.

关 键 词：心脏手术后 乳酸 影响因素 不良健康结局 

分 类 号：R654.2[医药卫生—外科学]