急性脑卒中重度瘫痪患者发生下肢深静脉血栓的影响因素分析  

Analysis of influencing factors for lower limb deep venous thrombosis in acute stroke patients complicated with severe paralysis

作　　者：周小菊 ZHOU Xiaoju(The Second Division of Department of Neurosurgery,the First Hospital of Longyan,Longyan 364000,Fujian Province,China)

机构地区：[1]福建省龙岩市第一医院神经外科二科,龙岩市364000

出　　处：《内科》2024年第6期601-606,共6页Internal Medicine

摘　　要：目的探讨急性脑卒中重度瘫痪患者发生下肢深静脉血栓(DVT)的影响因素。方法回顾性分析110例首发急性脑卒中重度瘫痪患者的临床资料,根据是否发生下肢DVT将患者分为DVT组(n=19)和非DVT组(n=91)。采用多因素logistic回归模型分析急性脑卒中重度瘫痪患者发生下肢DVT的危险因素。结果单因素分析结果显示,两组在年龄、吸烟史、房颤史、血栓史、意识状态、是否卧床≥72 h、是否使用脱水药物、是否留置中心静脉导管方面差异均有统计学意义(均P<0.05)。多因素logistic回归分析结果显示,年龄>60岁、吸烟、意识状态为昏迷、卧床≥72 h、使用脱水药物均为急性脑卒中重度瘫痪患者发生下肢DVT的危险因素(均P<0.05)。结论年龄>60岁、吸烟、昏迷、卧床≥72 h、使用脱水药物均为急性脑卒中重度瘫痪患者发生下肢DVT的危险因素,临床中应加强对该类患者的筛查,并采取针对性的预防措施,以降低DVT的发生风险。Objective To investigate the influencing factors for lower limb deep venous thrombosis(DVT)in acute stroke patients complicated with severe paralysis.Methods The clinical data of 110 patients with first-episode acute stroke complicated with severe paralysis were retrospectively analyzed,and the patients were divided into a DVT group(n=19)or a non-DVT group(n=91)according to whether the lower limb DVT had occurred.A multivariate logistic regression model was used to analyze the risk factors for lower limb DVT in acute stroke patients complicated with severe paralysis.Results The results of the univariate analysis showed that there were statistically significant differences in terms of age,smoking history,atrial fibrillation history,thrombosis history,state of consciousness,bed rest≥72 h or not,using dehydration drugs or not,and indwelling central venous catheter or not between the two groups(all P<0.05).The results of multivariate logistic regression analysis showed that age>60 years,smoking,with the state of consciousness being in a coma,bed rest≥72 h,and using dehydration drugs were risk factors for lower limb DVT in acute stroke patients complicated with severe paralysis(all P<0.05).Conclusion Age>60 years,smoking,coma,bed rest≥72 h,and using dehydration drugs are risk factors for lower limb DVT in acute stroke patients complicated with severe paralysis.Screening in such patients should be strengthened and targeted preventive measures should be taken in the clinical practice to reduce the occurrence risk of DVT.

关 键 词：急性脑卒中 重度瘫痪 深静脉血栓 下肢 危险因素 预防对策 

分 类 号：R743.3[医药卫生—神经病学与精神病学]