猕猴桃根苯丙素类化学成分研究  

Phenylpropanoids from Actinidia chinensis Planch.Radix

作　　者：梁光平 杨俊 万路平 梁玉清 韦德群 LIANG Guang-ping;YANG Jun;WAN Lu-ping;LIANG Yu-qing;WEI De-qun(Department of Pharmacy,Zunyi Medical and Pharmaceutical College,Zunyi 563006,China)

机构地区：[1]遵义医药高等专科学校药学系,贵州遵义563006

出　　处：《精细化工中间体》2025年第1期28-32,共5页Fine Chemical Intermediates

基　　金：贵州省科学技术基金项目(黔科合基础-ZK[2022]一般675号);贵州省“千”层次创新型人才培养项目(黔委人领办发[2022]3号)。

摘　　要：通过硅胶柱层析、Sephadex LH-20凝胶柱色谱以及半制备液相色谱技术对猕猴桃根二氯甲烷提取物的化学成分进行分离,所得化合物经MS、1H NMR、13C NMR鉴定其结构。结果表明,从猕猴桃根二氯甲烷提取物中分离得到13个苯丙素类化合物,分别鉴定为肉桂酸甲酯(■)、肉桂酸(■)、对羟基肉桂酸(■)、咖啡酸(■)、嗪皮啶(■)、异莨菪亭(■)、秦皮素(■)、秦皮乙素(■)、3,3'-bis(3,4-dihydro-4-hydroxy-6-methoxy-2H-1-benzopyran)(■)、4-oxopinoresinol(■)、rebaneolignan B(■)、4-羟基香豆素(■)、7-羟基香豆素(■)。其中,化合物■为首次从猕猴桃根中分离得到。The chemical constituents in the dichloromethane extract of Actinidia chinensis Planch.Radix were separated and purified through various chromatographic techniques,such as silica gel,Sephadex LH-20 and semipreparative HPLC.Then,the chemical structures were identified by MS,~1H NMR and~(13)C NMR.The results showed that thirteen phenylpropanoids in the dichloromethane extract of Actinidia chinensis Planch.Radix were isolated,which were identified as methyl cinnamate (■),cinnamic acid (■),4-hydroxycinnamic acid (■),caffeic acid (■),fraxidin (■),6-hydroxy-7-methoxycoumarin (■),fraxetin (■),esculetin (■),3,3'-bis(3,4-dihydro-4-hydroxy-6-methoxy-2H-1-benzopyran)(■),4-oxopinoresinol (■),rebaneolignan B (■),4-hydroxycoumarin (■),7-hydroxycoumarin (■).Compounds■were isolated from Actinidia chinensis Planch.Radix for the first time.

关 键 词：猕猴桃根 苯丙素 化学成分 分离鉴定 

分 类 号：TQ461[化学工程—制药化工] R914.5[医药卫生—药物化学]