症状性颅内动脉狭窄性急性脑梗死相关因素分析  

Analysis of related factors of symptomatic intracranial artery stenosis induced acute cerebral infarction

作　　者：李恒楠 孙晗 Li Hengnan;Sun Han(Yiwu Traditional Chinese Medicine Hospital,Yiwu,Zhejiang 322000,China)

机构地区：[1]浙江省义乌市中医医院,浙江义乌322000

出　　处：《首都食品与医药》2025年第2期36-39,共4页Capital Food Medicine

基　　金：义乌市科技局项目(编号:21-3-26)。

摘　　要：目的本研究旨在探讨症状性颅内动脉狭窄性急性脑梗死(SAICAS)患者的临床特征及与疾病发病相关的因素。方法共纳入293例患者,根据颅内动脉狭窄情况分为大脑中动脉狭窄组(153例)和非大脑中动脉狭窄组(140例)。所有患者均完成对颅脑MR、TOF/CTA等影像学检查,比较两组患者的年龄、性别、血压、低密度脂蛋白、高密度脂蛋白、血糖、同型半胱氨酸、NIHSS评分等。结果两组在性别、年龄等方面无显著差异(P>0.05)。综合所有大脑中动脉狭窄与非大脑中动脉狭窄的颅内动脉狭窄脑梗死,进一步进行年龄分组,分为A组(60岁以下)、B组(60-80岁)及C组(80岁以上)。通过对患者的性别、血压以及低密度脂蛋白、高密度脂蛋白、血糖、同型半胱氨酸、NIHSS评分进行比较分析,在生化指标方面,不同年龄组间的性别、舒张压、低密度脂蛋白、高密度脂蛋白、同型半胱氨酸指标存在差异(P<0.05),但对疾病严重程度(NIHSS评分)的影响不显著。结论颅内动脉狭窄脑梗死部位和年龄、性别无相关性,但随着年龄的变化,性别、舒张压、低密度脂蛋白、高密度脂蛋白、同型半胱氨指标方面出现明显变化。Objective This study aims to explore the clinical characteristics and factors associated with the onset of symptomatic intracranial arterial stenosis acute cerebral infarction(SAICAS)in patients.Methods A total of 293 patients were included and divided into a middle cerebral artery stenosis group(153 cases)and a non middle cerebral artery stenosis group(140 cases)based on the degree of intracranial artery stenosis.All patients completed imaging examinations such as cranial MR,TOF/CTA,and compared the age,gender,blood pressure,lowdensity lipoprotein,high-density lipoprotein,blood glucose,homocysteine,NIHSS score,etc.between the two groups of patients.Results No significant differences were found between the two groups in terms of gender,age,etc.(P>0.05).Based on a comprehensive comparison of all intracranial artery stenosis stroke cases with and without middle cerebral artery stenosis,further age groups were divided into Group A(under 60 years old),Group B(60-80 years old),and Group C(over 80 years old).By comparing and analyzing the gender,blood pressure,low-density lipoprotein,high-density lipoprotein,blood glucose,homocysteine,and NIHSS scores of patients,it was found that there were differences in biochemical indicators between different age groups in terms of gender,diastolic blood pressure,low-density lipoprotein,highdensity lipoprotein,and homocysteine scores(P<0.05),but the impact on disease severity(NIHSS score)was not significant.Conclusion There is no correlation between the location of intracranial artery stenosis and cerebral infarction,age,or gender.But with age,there are significant changes in gender,diastolic blood pressure,low-density lipoprotein,high-density lipoprotein,and homocysteine indicators.

关 键 词：颅内动脉狭窄性 急性脑梗死 相关因素 

分 类 号：R743.33[医药卫生—神经病学与精神病学]