联合检验肌酸激酶同工酶MB、肌红蛋白以及心肌肌钙蛋白I对心肌梗死患者诊断效能的影响  

The impact of combined testing of creatine kinase-MB,myoglobin,and cardiac troponin I on the diagnostic efficiency for myocardial infarction patients

作　　者：李娟 赖丽思 郭圳旋 Li Juan;Lai Lisi;Guo Zhenxuan(Huizhou Sixth People’s Hospital,Huizhou,Guangdong 516211,China;Shenhe People’s Hospital,Heyuan,Guangdong 517600,China)

机构地区：[1]广东省惠州市第六人民医院,广东惠州516211 [2]广东省河源市深河人民医院,广东河源517600

出　　处：《首都食品与医药》2025年第1期87-89,共3页Capital Food Medicine

摘　　要：目的分析联合检验肌酸激酶同工酶MB(CK-MB)、肌红蛋白(MYO)以及心肌肌钙蛋白I(cTnI)对心肌梗死患者诊断效能的影响。方法选取2024年1-5月期间我院收治的胸痛疑似心肌梗死患者97例,所有患者均进行CK-MB、MYO、cTnI检验,以冠状动脉造影检测结果为金标准;比较CK-MB、MYO、cTnI单独和联合检验的诊断效能。结果97例胸痛患者中,急性心肌梗死有84例,不稳定型心绞痛有13例;联合检验的灵敏度(96.43%)、特异度(92.31%)、准确度(95.88%)均高于单一检验。结论在心肌梗死患者的诊断过程中,结合使用CK-MB、MYO、cTnI等多种生物标志物进行联合检验,能够显著提升诊断的准确性和效率,为临床决策提供更为全面和可靠的信息,值得推广与应用。Objective To analyze the impact of combined testing of creatine kinase-MB(CK-MB),myoglobin(MYO),and cardiac troponin I(cTnI)on the diagnostic efficiency for patients with myocardial infarction.Methods From January to May 2024,97 patients with chest pain suspected of myocardial infarction were selected in our hospital.All patients underwent CK-MB,MYO,and cTnI tests,with coronary angiography results as the gold standard.The diagnostic efficiency of CK-MB,MYO,and cTnI was compared both individually and in combination.Results Among the 97 patients with chest pain,84 had acute myocardial infarction,and 13 had unstable angina.The sensitivity(96.43%),specificity(92.31%),and accuracy(95.88%)of the combined tests were higher than those of individual tests.Conclusion In the diagnosis of myocardial infarction,the combined use of biomarkers such as CK-MB,MYO,and cTnI significantly enhances diagnostic accuracy and efficiency.This provides more comprehensive and reliable information for clinical decision-making and is worth promoting and applying.

关 键 词：联合检验 CK-MB MYO CTNI 心肌梗死 诊断效能 影响 

分 类 号：R542.22[医药卫生—心血管疾病]