supported by The Youth Innovation Promotion Association,CAS,and Key Clinical Projects of Peking University Third Hospital(no.BYSYZD2023004);This study was conducted with approval from the Peking University Third Hospital Medical Science Research Ethics Committee(no.M2021091);all patients were fully informed and provided written consent prior to participation.
Muscle strength(MS)is related to our neural and muscle systems,essential for clinical diagnosis and rehabilitation evaluation.Although emerging wearable technology seems promising for MS assessment,problems still exis...
In this manuscript, we present a case report of a child with 16-year-old previously healthy Hispanic male who presented for progressive proximal muscle weakness, rash, and dysphagia. He was admitted to the acute care ...
supported by National Science Fund for Distinguished Young Scholars(82225014);the Science and Technology Commission of Shanghai Municipality(21JC1401000);the Ministry of Science and Technology of China(2021YFA1101302,2020YFA0908201);the National Natural Science Foundation of China(82192860,82171148,82201306);the China Postdoctoral Science Foundation(2022M720780);the Shanghai Municipal Health Commission(20224Z0003);the Science and Technology Commission of Shanghai Municipality(21S11905100 and 23J31900100);the Shanghai Municipal Education Commission(2023ZKZD12);the Shanghai Clinical Medical Research Center for Otolaryngology Diseases(20MC1920200);the science and technology innovation program of Hunan Province(2023RC4005);the Shuguang Program(20SG08)supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation,and Fudan University(yg2022-23).
Adeno-associated virus(AAV)-mediated gene therapy is widely applied to treat numerous hereditary diseases in animal models and humans.The specific expression of AAV-delivered transgenes driven by cell type-specific pr...