Adolescent-Onset Triple-Antibody Positive Juvenile Dermatomyositis Found in Hispanic Male Wrestler: A Case Report and Literature Review  

作　　者：Rajvee Sanghavi Patrycja Tesmer Deepika Singh Sukesh Sukumaran Rajvee Sanghavi;Patrycja Tesmer;Deepika Singh;Sukesh Sukumaran(Department of Pediatrics, Valley Childrens Hospital, Madera, CA, USA;School of Medicine, Stanford University, Stanford, CA, USA)

机构地区：[1]Department of Pediatrics, Valley Childrens Hospital, Madera, CA, USA [2]School of Medicine, Stanford University, Stanford, CA, USA

出　　处：《Open Journal of Rheumatology and Autoimmune Diseases》2025年第1期36-42,共7页风湿病与自身免疫疾病期刊(英文)

摘　　要：In this manuscript, we present a case report of a child with 16-year-old previously healthy Hispanic male who presented for progressive proximal muscle weakness, rash, and dysphagia. He was admitted to the acute care floor and diagnosed with juvenile dermatomyositis and found to be positive for anti-Mi-2 alpha, anti-Mi-2 beta, and anti-MDA-5 antibodies. He gradually improved with a combination of steroid, immunomodulatory treatment, and physical therapy. This case outlines the clinical course of a patient with this rare disorder as well as the importance of understanding the role of associated antibodies to manage potential long-term sequelae.In this manuscript, we present a case report of a child with 16-year-old previously healthy Hispanic male who presented for progressive proximal muscle weakness, rash, and dysphagia. He was admitted to the acute care floor and diagnosed with juvenile dermatomyositis and found to be positive for anti-Mi-2 alpha, anti-Mi-2 beta, and anti-MDA-5 antibodies. He gradually improved with a combination of steroid, immunomodulatory treatment, and physical therapy. This case outlines the clinical course of a patient with this rare disorder as well as the importance of understanding the role of associated antibodies to manage potential long-term sequelae.

关 键 词：Juvenile Dermatomyositis Myositis-Associated Antibodies Myositis-Specific Antibodies 

分 类 号：R73[医药卫生—肿瘤]