妥布霉素地塞米松眼膏联合泪道U形置管术治疗上泪道阻塞的临床效果  

Clinical Effect of Tobramycin and Dexamethasone Ophthalmic Ointment Combined with U-shaped Catheterization of Lacrimal Passage in the Treatment of Upper Lacrimal Passage Obstruction

作　　者：张铮 郑波涛 韦舒怡 黎畅 李超[1] ZHANG Zheng;ZHENG Botao;WEI Shuyi;LI Chang;LI Chao(Suzhou Kowloon Hospital,Suzhou 215000,China;不详)

机构地区：[1]苏州九龙医院,江苏苏州215000 [2]苏州工业园区星塘医院

出　　处：《中外医学研究》2025年第5期67-70,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究妥布霉素地塞米松眼膏联合泪道U形置管术治疗上泪道阻塞患者的临床效果。方法:选取2019年1月—2023年12月苏州九龙医院眼科收治的100例上泪道阻塞患者作为研究对象,随机分为研究组(n=50)与对照组(n=50)。研究组给予妥布霉素地塞米松眼膏联合泪道U形置管术治疗,对照组给予泪道U形置管术治疗,比较两组临床疗效、泪液分泌量、泪膜破裂时间、并发症发生率。结果:研究组临床总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组泪液分泌量比较,差异无统计学意义(P>0.05);拔除留置U型管3个月后,两组泪液分泌量少于治疗前,且研究组少于对照组,差异有统计学意义(P<0.05);两组治疗前、拔除留置U型管3个月后泪膜破裂时间比较,差异无统计学意义(P>0.05)。研究组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:上泪道阻塞患者采用妥布霉素地塞米松眼膏联合泪道U形置管术治疗效果显著,可减少泪液分泌量,并发症发生率较低。Objective:To explore the clinical effect of Tobramycin and Dexamethasone Ophthalmic Ointment combined with U-shaped catheterization of lacrimal passage in the treatment of patients with upper lacrimal passage obstruction.Method:A total of 100 patients with upper lacrimal passage obstruction who admitted to the Department of Ophthalmology of Suzhou Kowloon Hospital from January 2019 to December 2023 were selected as the study objects,they were randomly divided into the study group(n=50)and the control group(n=50).The study group was treated with Tobramycin and Dexamethasone Ophthalmic Ointment combined with U-shaped catheterization of lacrimal passage,and the control group were treated with U-shaped catheterization of lacrimal passage,the clinical efficacy,tear secretion,tear film rupture time and complication rate were compared between two groups.Result:The total clinical effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in the tear secretion between two groups(P>0.05);after 3 months of removal of indwelling U-shaped tube,the tear secretion of two groups were less than those before treatment,and that of the study group was less than that of the control group,the difference was statistically significant(P<0.05).There were no significant differences in the tear film rupture time between two groups before treatment and after 3 months of removal of indwelling U-shaped tube(P>0.05).The complication rate of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:The effect of Tobramycin and Dexamethasone Ophthalmic Ointment combined with U-shaped catheterization of lacrimal passage in the treatment of patients with upper lacrimal duct obstruction is significant,which can reduce the amount of tear secretion and the incidence of complications is low.

关 键 词：妥布霉素地塞米松眼膏 泪道U 形置管术 上泪道阻塞 

分 类 号：R779.6[医药卫生—眼科]