微生物代谢途径的基因工程改造及应用研究  

Research on Genetic Engineering and Application of Microbial Metabolic Pathways

作　　者：张恬嘉 ZHANG Tianjia(Qingdao University,Yantai 266000,China)

机构地区：[1]青岛大学,山东烟台266000

出　　处：《工业微生物》2025年第1期71-73,共3页Industrial Microbiology

摘　　要：文章旨在探讨基因工程改造微生物代谢途径的方法及其在工业和药物生产领域的实际应用。同时,通过分析微生物代谢途径所面临的现状与挑战,揭示了基因工程改造的必要性和潜在优势,并详细介绍了基因克隆与表达系统、代谢通路调控策略和高通量技术的应用。此外,还通过实际应用案例展示了基因工程在提高谷氨酸和青霉素产量方面的显著成效。The article explores the methods for genetic engineering modification of microbial metabolic pathways and its practical applications in industrial and pharmaceutical production.By analyzing the current status and challenges of microbial metabolic pathways,the necessity and potential advantages of genetic engineering modification are pointed out,and the gene cloning and expression system,metabolic pathway regulation strategy,and high-throughput technology are introduced in detail.In addition,practical application cases demonstrate the significant effectiveness of genetic engineering in increasing the production of glutamate and penicillin.

关 键 词：基因工程 微生物代谢 代谢通路调控 高通量技术 工业应用 

分 类 号：Q935[生物学—微生物学] Q78