皮肤鸟分枝杆菌复合体感染合并基底细胞癌1例  

Cutaneous Mycobacterium Avium Complex Infection Complicated by Basal Cell Carcinoma:A Case Report

作　　者：李琳[1] 司晴晴 张龙飞 赵好 黄茜 孙东杰[1] LI Lin;SI Qingqing;ZHANG Longfei;ZHAO Hao;HUANG Qian;SUN Dongjie(Department of Dermatology,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,China)

机构地区：[1]昆明医科大学第一附属医院皮肤科,云南昆明650032

出　　处：《中国皮肤性病学杂志》2025年第3期310-313,共4页The Chinese Journal of Dermatovenereology

基　　金：云南省“兴滇英才支持计划”名医专项(XDYC-MY-2022-0067);云南省皮肤与免疫性疾病临床医学中心(ZX2019-03-02)。

摘　　要：患者女,59岁,左面部暗红斑、结节、破溃结痂伴痛9个月。皮肤科情况:左侧面部见一片状暗红斑,浸润、压痛明显,其上覆黄豆至钱币大小黄黑色痂,其下见多发溃疡,可挤出少量脓液。左耳前、下颌处分别见一花生和蚕豆大小囊肿。分泌物和组织DNA测序鉴定为鸟分枝杆菌复合体感染。予克拉霉素、利福喷丁、乙胺丁醇、苯扎氯氨溶液湿敷治疗。2个月后患者复诊,原有皮损大部分消退,无新发皮损。左侧面部皮损区域查见一褐色丘疹,病理检查确诊褐色丘疹皮损为基底细胞癌。A 59-year-old female presented with dark erythema,nodules,ulceration and scab on the left face with pain for 9 months.Dermatological examination showed a patch of dark erythema on the left face,with infiltration and tenderness.It was covered with yellow and black scab of soybean to coin size.Multiple ulcers were seen under it,and a small amount of pus could be extrudated.A peanut-and bean-sized cyst was found in front of the left ear and mandible.Secretion and tissue DNA sequencing identified Mycobacterium avium complex infection.She was treated with clarithromycin,rifampicin,ethambutol and benzalchloramine.Two months later,the patient returned,and most of the original skin lesions subsided,and no new skin lesions appeared.A brown papule appeared in the lesion area.Pathological examination confirmed the brown papule as basal cell carcinoma.

关 键 词：鸟分枝杆菌复合体 基底细胞癌 

分 类 号：R739.5[医药卫生—肿瘤] R754[医药卫生—临床医学]