急性缺血性脑卒中患者机械取栓后医院感染直接经济负担  

Analysis of hospital-acquired infection and direct economic burden after mechanical thrombectomy for patients with acute ischemic stroke

作　　者：龚小沉 唐宇凤 李肇坤 邹新宇 陆婷婷 GONG Xiaochen;TANG Yufeng;LI Zhaokun;ZOU Xinyu;LU Tingting(Mianyang Central Hospital,School of Medicine,University of Electronic Science and Technology of China,Mianyang,Sichuan 621000,China)

机构地区：[1]电子科技大学医学院附属绵阳医院·绵阳市中心医院神经内科,四川绵阳621000 [2]电子科技大学医学院附属绵阳医院·绵阳市中心医院感染管理科,四川绵阳621000

出　　处：《中华医院感染学杂志》2025年第3期456-459,共4页Chinese Journal of Nosocomiology

基　　金：四川省医学会基金资助项目(S21023)。

摘　　要：目的评估急性缺血性脑卒中患者机械取栓后医院感染及其直接经济负担,以指导临床用药。方法对2021年1月1日—2022年12月31日收治在神经内科的急性缺血性脑卒中机械取栓患者236例开展医院感染调查,收集分析患者的基本信息、临床治疗、医院感染危险因素、住院费用等资料;以是否发生医院感染作为分组依据,将患者分为医院感染组21例和非医院感染组215例,比较两组患者的住院天数和住院费用。结果共纳入急性缺血性脑卒中机械取栓患者236例,发生医院感染21例,医院感染发病率为8.90%,以下呼吸道感染为主。医院感染组患者住院时间中位数为17天,非医院感染组患者住院时间中位数为11天,因医院感染延长的住院天数为6天,两组差异有统计学意义(P=0.035)。医院感染组患者住院总费用中位数为119020.47元,非医院感染患者组住院总费用中位数为93553.98元,医院感染导致患者的直接经济负担为25466.49元,两组住院费用差异有统计学意义(P=0.035)。结论急性缺血性脑卒中机械取栓患者发生医院感染不仅会导致患者住院时间延长,降低科室床位周转率,且会导致患者住院费用增加,给患者带来沉重的经济负担,增加医疗成本,给医院带来经济负担。OBJECTIVE To assess hospital-acquired infections and their direct economic burden after mechanical thrombectomy for patients with acute ischemic stroke in order to guide clinical medication.METHODS A hospitalacquired infection survey was conducted on 236 patients with acute ischemic stroke underwent mechanical thrombectomy admitted to the department of neurology from Jan.1,2021 to Dec.31,2022,the patients'basic information,clinical treatments,hospital-acquired infection-related risk factors,costs of hospitalization,and other relevant variables were collected and analyzed.Based on whether or not occurring hospital-acquired infection,the patients were divided into 21 cases of the hospital-acquired infection group and 215 cases of the non-hospital-acquired infection group,and the hospitalization days and expenses of the two groups were compared.RESULTS A total of 236 acute ischemic stroke patients who underwent mechanical thrombectomy were included,and 21 cases acquired infections,with an incidence rate of 8.90%,and lower respiratory tract infections predominated.The median length of hospitalization was 17 days for patients in the hospital-acquired infection group and 11 days in the nonhospital-acquired infection group.There was 6 days for prolonged hospitalization due to hospital-acquired infections,and the difference was statistically significant(P=0.035).The median total hospitalization cost for patients in the hospital-acquired infection group was 119020.47 yuan,and in the non-hospital-acquired infection group was 93553.98 yuan.The direct economic burden for patients due to hospital-acquired infections was 25466.49 yuan with a statistically significant difference between the two groups(P=0.035).CONCLUSIONS Hospital-acquired infections in acute ischemic stroke patients undergoing mechanical thrombectomy not only lead to prolonged hospitalization time and reduc departmental bed turnover rates,but also resulted in an increased hospitalization costs,which will bring a heavy economic burden to the patients,increase t

关 键 词：急性缺血性脑卒中 机械取栓 医院感染 术后感染 经济负担 

分 类 号：R743.3[医药卫生—神经病学与精神病学]