Asymmetric construction of axial and planar chirality with N-heterocyclic carbene(NHC)organocatalysis  

作　　者：Meng Zhang Xiaoqun Yang Xiaolin Peng Xiangyang Li Zhichao Jin 

机构地区：[1]State Key Laboratory of Green Pesticide,Guizhou University,Guiyang 550025,China

出　　处：《Science China Chemistry》2025年第3期815-825,共11页中国科学(化学英文版)

基　　金：supported by the National Natural Science Foundation of China (22371057,32172459,32330087);the National Key Research and Development Program of China (2022YFD-1700300);the Science and Technology Department of Guizhou Province (Qiankehejichu-ZK (2021)Key033);the Frontiers Science Center for Asymmetric Synthesis and Medicinal Molecules,Department of Education,Guizhou Province (Qianjiaohe KY (2020)004);the Central Government Guides Local Science and Technology Development Fund Projects (Qiankehezhongyindi (2024)007, (2023)001);the Program of Major Scientific and Technological,Guizou Province (Qiankehechengguo (2024)zhongda007);the Program of Introducing Talents of Discipline to Universities of China (111 Program,D20023)at Guizhou University;the Yongjiang Plan for Innovation and Entrepreneurship Leading Talent Project in the City of Nanning (2021005);Guizhou University (China)。

摘　　要：N-heterocyclic carbene(NHC)organocatalytic reactions that have been developed for asymmetric construction of axial and planar chirality are systematically summarized and discussed in this review.The challenges and limitations inherent to this highly reactive research field are highlighted towards the end of the review.Additionally,based on our understanding of the current advancements in NHC organocatalysis,we propose potential future directions for further exploration.

关 键 词：N-heterocyclic carbene axial chirality planar chirality asymmetric synthesis ORGANOCATALYSIS 

分 类 号：O621.251[理学—有机化学]