Intrathymic alloantigen expression——the Holy Grail or reinventing the wheel?  

作　　者：Gavin J.Pettigrew 

机构地区：[1]Department of Surgery,University of Cambridge,Cambridge,UK

出　　处：《Cell Research》2025年第2期87-88,共2页细胞研究(英文版)

摘　　要：In clinical solid organ transplantation,strategies that achieve long-term immunosuppression-free graft survival without the need for intense myeloablative conditioning remain elusive.In this issue of Cell Research,Liu et al.report that in murine transplant model,central deletional tolerance achieved by transduction of donor MHC alloantigen expression on the recipient thymus results in long-term skin allograft survival.

关 键 词：CLINICAL DONOR 

分 类 号：R392[医药卫生—免疫学]