慢性意识障碍神经调控治疗进展  

Advances in neuromodulation for treatment of prolonged disorders of consciousness

作　　者：何晨 宋明 徐珑[1,3] HE Chen;SONGMing;XU Long(Center of Neurosurgery,Beijing Tiantan Hospital,Beijing 100070,China;Laboratory of Brain Atlas and Brain-inspired Intelligence,Brainnetome Center,Institute of Automation Chinese Academy of Sciences,Beijing 100190,China;China National Clinical Research Center for Neurological Disease,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院神经外科学中心,100070 [2]国家神经系统疾病临床医学研究中心,北京100070 [3]中国科学院自动化研究所脑图谱与类脑实验室脑网络组研究中心,北京100190

出　　处：《中国现代神经疾病杂志》2025年第1期48-56,共9页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：国家科技创新2030-“脑科学与类脑研究”重大项目(项目编号:2021ZD0204203)。

摘　　要：神经调控技术已成为慢性意识障碍患者的重要临床治疗方法,包括非侵入性和侵入性技术。本文整合意识形成和恢复的神经机制、脑功能评估工具,并分类介绍非侵入性和侵入性神经调控技术的应用现状和新近研究成果,以期提高神经调控治疗的科学性和有效性,为慢性意识障碍患者的治疗提供更有力支持。Neuromodulation has emerged as a significant clinical treatment modality for patients with prolonged disorders of consciousness(pDOC),encompassing both non-invasive and invasive neuromodulation techniques.This paper integrates an overview of the neural mechanisms underlying consciousness,neurofunctional assessments,and categorizes the current applications and recent research findings in non-invasive and invasive neuromodulation techniques.The aim is to enhance the scientific rigor and efficacy of neuromodulation,provide robust support for the treatment of pDOC.

关 键 词：意识障碍 物理刺激 电刺激疗法 综述 

分 类 号：R741[医药卫生—神经病学与精神病学]