精神疾病神经调控治疗进展  

Progress on neuromodulation for treatment of mental disorders

作　　者：董文文 邱畅 赵亮 章文斌[1] DONG Wen-wen;QIU Chang;ZHAO Liang;ZHANG Wen-bin(Department of Functional Neurosurgery,The Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029,Jiangsu,China)

机构地区：[1]南京医科大学附属脑科医院功能神经外科,210029

出　　处：《中国现代神经疾病杂志》2025年第1期57-64,共8页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：江苏省重点研发计划产业前瞻与关键技术研发项目(项目编号:BE2022049);江苏省重点研发计划产业前瞻与关键技术研发项目(项目编号:BE2022049-1)。

摘　　要：精神疾病传统治疗方法包括药物治疗和心理治疗,但部分患者无法有效控制症状。神经调控技术主要分为侵入性或非侵入性,对神经回路进行干预可改善精神疾病患者精神症状。本文对强迫症、抑郁症、抽动秽语综合征、双相情感障碍、孤独症谱系障碍、物质依赖及精神分裂症等精神疾病所用神经调控技术的应用现状进行总结,并分析神经调控技术在精神疾病治疗中的前景及挑战,以指导未来精神疾病的神经调控治疗。Traditional treatment methods for mental disorders include pharmacotherapy and psychotherapy.However,some patients are unable to effectively control their symptoms.Neuromodulation technique,which can be implemented through invasive or non-invasive approaches,have shown promise in improving the psychiatric symptoms of individuals with mental illnesses by intervening in neural circuits.This paper summarizes the current applications of neuromodulation technique for various mental disorders,including obsessive-compulsive disorder,depression,Tourette's syndrome,bipolar affective disorder,autism spectrum disorder,substance dependence and schizophrenia.Additionally,it analyzes the prospects and challenges of neuromodulation technique in the treatment of mental disorders,with the aim of guiding future neuromodulation therapy for mental disorders.

关 键 词：精神障碍 物理刺激 经颅磁刺激 深部脑刺激法 综述 

分 类 号：R749[医药卫生—神经病学与精神病学]