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作 者:桂超 尹玉婷 GUI Chao;YIN Yuting(Hubei Cancer Hospital,Wuhan 430079,China)
出 处:《中国实用神经疾病杂志》2025年第4期432-436,共5页Chinese Journal of Practical Nervous Diseases
基 金:武汉市知识创新专项基础研究项目(编号:2022020801010511)。
摘 要:目的总结小脑血管母细胞瘤的临床特征及显微手术技巧。方法回顾性分析湖北省肿瘤医院手术治疗的39例小脑血管母细胞瘤患者的临床资料,经颅脑MRI分型,囊壁结节型19例,囊实型12例,实体型8例,分析总结其临床表现、影像学特征、手术效果。结果39例患者肿瘤全切,术后脑脊液漏2例,脑积水2例经脑室外引流恢复;31例术后头痛、眩晕、呕吐症状明显好转,8例症状有所改善,未出现死亡。术后随访3个月~1 a,未见复发。结论小脑血管母细胞瘤临床症状以小脑平衡功能障碍及眩晕、呕吐为主,治疗首选手术切除,针对不同类型血管母细胞瘤采取不同手术策略。实体性肿瘤手术难度大,对大型实体性血管母细胞瘤术前栓塞有助于手术全切。Objective To analyze the clinical features and surgical treatment of cerebellar hemangioblastomas.Methods The data of 39 cases with cerebellar hemangioblastomas were analyzed retrospectively,according to their MRI features,the tumors were divided into three types:19 cases were large cystic with small nodule,12 cases were solid and cystic,8 cases were entity solid.The clinical feature,imaging characteristics,surgical effect were summarized.Results All 39 cases were completely resection,after operation,2 cases had cerebrospinal fluid leakage and recovered after symptomatic treatment,2 cases had hydrocephalus and recovery by external ventricular drainage,31 cases with dizziness and vertigo symptoms improved markedly,symptoms improved in 8 patients,no patients died of the operation,the patients were followed up for 3 months to 1 year,no recurrence was found.Conclusion The clinical symptoms of cerebellar hemangioblastoma are mainly cerebellar balance dysfunction,dizziness and vomiting.Surgical resection is the first treatment,different surgical strategies for different types of hemangioblastomas.Solid tumors are difficult to operate,preoperative embolization is helpful for total resection of large solid hemangioblastomas.
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