超声造影评估颈动脉斑块新生血管联合ABCD3-Ⅰ评分对TIA早期发生脑卒中风险的预测价值  

Predictive value of contrast-enhanced ultrasound assessment of carotid plaque neovascularization combined with ABCD3Ⅰ-for early stroke risk in TIA patients

作　　者：曹蕾[1] 韩翠萍[1] 张永亭 CAO Lei;HAN Cuiping;ZHANG Yongting(Zibo Mental Health Center/The Fifth People’s Hospital of Zibo,Zibo 255100,China)

机构地区：[1]淄博市精神卫生中心淄博市第五人民医院,山东淄博255100

出　　处：《中国实用神经疾病杂志》2025年第4期458-461,共4页Chinese Journal of Practical Nervous Diseases

基　　金：2023年度淄博市医药卫生科研项目(编号:20230310034)。

摘　　要：目的探讨超声造影评估颈动脉斑块新生血管联合ABCD3-Ⅰ评分对短暂性脑缺血发作(TIA)早期发生脑卒中风险的预测价值。方法纳入2020-06—2023-06淄博市第五人民医院收治的175例TIA患者为研究对象,依据是否发生脑卒中分为未发病组(n=100)与发病组(n=75)。所有患者均进行超声造影评估颈动脉斑块新生血管,并进行ABCD3-Ⅰ量表评估。采用受试者工作特征(ROC)曲线评估预测价值。结果发病组患者ABCD3-Ⅰ评分中高危、中危患者比例明显高于未发病组(P<0.05),颈动脉斑块新生血管三、四级比例明显高于未发病组(P<0.05)。超声造影评估颈动脉斑块新生血管的曲线下面积(AUC)、灵敏度及特异度分别为0.782、0.812及0.806,ABCD3-Ⅰ评分预测的AUC、灵敏度及特异度分别为0.691、0.800及0.796,两项指标联合检测的AUC、灵敏度及特异度分别为0.844、0.865及0.815。结论颈动脉斑块新生血管超声造影及ABCD3-Ⅰ评分对TIA早期发生脑卒中有一定的预测价值,两者联用诊断价值更高。Objective To investigate the predictive value of contrast-enhanced ultrasound assessment of carotid plaque neovascularization combined with ABCD3-Ⅰfor early stroke risk in TIA patients.Methods Totally 175 TIA patients admitted to the Fifth People’s Hospital of Zibo from June 2020 to June 2023 were included as the research subjects,and were divided into the non-onset group(n=100)and the onset group(n=75)based on whether stroke occurred.All the patients underwent contrast-enhanced ultrasound assessment of carotid artery plaque neovascularization and were given ABCD3-Ⅰassessment.The predictive value was evaluated using receiver operating characteristic(ROC)curve.Results The proportion of high risk and medium risk patients in the ABCD3-Ⅰscore of the onset group was significantly higher than that of the non-onset group(P<0.05).The proportion of 3 and 4 degree neovascularization of carotid artery plaques in the onset group was significantly higher than that in the non-onset group(P<0.05).The AUC,and sensitivity and specificity of carotid artery plaque neovascularization evaluated by contrast-enhanced ultrasound was 0.782,0.812,and 0.806,respectively,which of the ABCD3-Ⅰscore was 0.691,0.800,and 0.796,respectively.The AUC,sensitivity,and specificity of the two indicators combined was 0.844,0.865,and 0.815,respectively.Conclusion Carotid plaque neovascularization contrast-enhanced ultrasound and ABCD3-Ⅰscore have certain predictive value for early stroke in TIA patients,and the diagnostic value of combination is higher.

关 键 词：短暂性脑缺血发作 脑卒中 超声造影 颈动脉斑块 ABCD3-Ⅰ评分 

分 类 号：R743.31[医药卫生—神经病学与精神病学]