基于肺与大肠相表里探讨肺肠同治调节脓毒症免疫功能紊乱  

Exploring combined treatment of sepsis immune dysfunction based on lung and intestine

作　　者：刘艺 姬泉雅 吴彩军 Liu Yi;Ji Quanya;Wu Caijun(Department of Emergency Medicine,Dongzhimen Hospital of Beijing University of Chinese Medicine,Beijing 100700,China;Institute of Sepsis,Beijing University of Chinese Medicine,Beijing 100700,China;Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine,Beijing 100070,China)

机构地区：[1]北京中医药大学东直门医院急诊科,北京100700 [2]北京中医药大学脓毒症研究所,北京100700 [3]北京中医药大学东直门医院,北京100070

出　　处：《中国医师杂志》2025年第2期184-188,共5页Journal of Chinese Physician

基　　金：国家中医药管理局应急研究专项(2023ZYLCYJ02-1)。

摘　　要：脓毒症病死率高,病理机制非常复杂,免疫功能紊乱在其中发挥了重要作用。肺和肠道在生理上相互为用,病理上互相影响,定居于二者黏膜表面的微生物群与免疫功能紧密联系,为肺肠同治调节脓毒症免疫功能紊乱、降低脓毒症病死率和改善长期预后提供了理论和物质基础。Sepsis has a high mortality rate and a very complex pathological mechanism,in which immune dysfunction plays an important role.The lung and intestine interact physiologically and pathologically.The microflora residing on the mucosal surface of the two are closely related to immune function,which provides a theoretical and material basis for the combined treatment of lung and intestine to regulate immune dysfunction in sepsis,reduce sepsis mortality and improve long-term prognosis.

关 键 词：脓毒症 免疫功能 肺 肠道 

分 类 号：R73[医药卫生—肿瘤]