IgA肾病遗传性的中西医研究进展  

Research Progress of Traditional Chinese and Western Medicine on Heritability of IgA Nephropathy

作　　者：冯琦 张少卿(指导)[2] 张君[2] FENG Qi;ZHANG Shaoqing;ZHANG Jun(Grade 2022 Graduate,Liaoning University of Traditional Chinese Medicine,Liaoning Province,Shenyang 110032,China;Department of Pediatrics,Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Liaoning Province,Shenyang 110031,China;Pediatrics of Traditional Chinese Medicine,The First Clinical College,Liaoning Province,Shenyang 110032,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110032 [2]辽宁中医药大学附属医院儿科,辽宁沈阳110031

出　　处：《光明中医》2025年第3期601-604,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：中医药行业科研专项(No.201507001-03);张君全国名老中医传承工作室。

摘　　要：IgA肾病(IgAN)是儿童较为常见的原发性肾小球疾病,也是导致肾小球肾炎和肾脏功能衰竭的主要原因之一。其病名在中医古籍上并无明确记载,但根据临床症状常归属于“尿血、水肿、虚劳”等范畴。研究证实,IgAN的发生与遗传学调控异常相关。因此,通过基因组学和对中医体质研究来分析IgAN的遗传学特点,进而完善IgAN的发病机制以指导临床治疗,改善预后和降低疾病发生十分必要。文章从中西医的角度对IgAN遗传学的研究进行了归纳总结,旨对今后研究此方向奠定基础。IgA nephropathy(IgAN)is a common primary glomerular disease in children and one of the main causes of glomerulonephritis and kidney failure.The name of the disease is not clearly recorded in ancient traditional Chinese medicine(TCM)books,but according to clinical symptoms,it is often considered as“hematuria”,“edema”,“consumptive disease”and other categories.Studies have confirmed that the occurrence of IgAN is related to abnormal genetic regulation.Therefore,it is very necessary to analyze the genetic characteristics of IgAN and improve the pathogenesis of IgAN to guide clinical treatment,improve prognosis and reduce the occurrence of disease through genomics and the study of TCM constitution.This paper summarized the research on IgAN genetics from the perspective of traditional Chinese and Western medicine,aiming to lay a foundation for future research in this direction.

关 键 词：虚劳 IGA肾病 遗传性 中西医 

分 类 号：R692.31[医药卫生—泌尿科学]