经颅磁刺激联合肌肉牵伸技术在帕金森病患者肌强直中的应用效果  

Application effect of repetitive transcranial magnetic stimulation combined with muscle stretching technique in myotonia in patients with Parkinson′s disease

作　　者：殷美霞 魏文娟 吕小薇 YIN Meixia;WEI Wenjuan;LYU Xiaowei(Department of Neurology,Jiujiang University Affiliated Hospital,Jiangxi Province,Jiujiang 332000,China)

机构地区：[1]九江学院附属医院神经内科,江西九江332000

出　　处：《中国当代医药》2025年第4期165-169,共5页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202410700)。

摘　　要：目的探讨经颅磁刺激(rTMS)联合肌肉牵伸技术在帕金森病(PD)患者肌强直中的应用效果。方法选取2023年1月至2024年4月九江学院附属医院收治的80例PD患者的临床资料进行回顾性分析,按照干预手段的不同分为对照组(40例)和观察组(40例)。对照组予以rTMS干预,观察组加用肌肉牵伸技术,两组患者均持续干预3周。比较两组患者肌强直严重程度、步行能力和肌张力。结果干预前,两组患者帕金森病统一评分量表第三部分(UPDRS-Ⅲ)、肌张力评定量表(TAS)评分、10米步行测试所用时间比较,差异无统计学意义(P>0.05);干预后,两组患者UPDRS-Ⅲ、TAS评分均低于本组干预前,10米步行测试所用时间均短于干预前,且观察组UPDRS-Ⅲ、TAS评分低于对照组,且观察组10米步行测试所用时间短于对照组,差异有统计学意义(P<0.05)。结论rTMS联合肌肉牵伸技术可改善PD患者肌强直症状、步行能力和肌张力,是一种理想的干预手段,值得临床推广应用。Objective To investigate the effect of repetitive transcranial magnetic stimulation(rTMS)combined with muscle stretching technique on myotonia in patients with Parkinson's disease(PD).Methods The clinical data of 80 PD patients admitted to Jiujiang University Affiliated Hospital from January 2023 to April 2024 were retrospectively analyzed,and they were divided into control group(40 cases)and observation group(40 cases)according to different intervention methods.The control group was treated with rTMS intervention,and the observation group was treated with muscle stretching technique.Both groups were continuously treated for 3 weeks.The severity of myotonia,walking ability and muscle tone were compared between the two groups.Results Before intervention,there were no significant differences between the two groups in unified Parkinson disease rating scale partⅢ(UPDRS-Ⅲ),tension rating scale(TAS)score and the time spent on 10-meter walking test(P>0.05).After intervention,UPDRS-Ⅲ and TAS scores in both groups were lower than those before intervention,and the duration of 10-meter walking test were shorter than those before intervention,and the UPDRS-Ⅲ and TAS scores in the observation group were lower than those in the control group,and the duration of 10-meter walking test in the observation group was shorter than that in the control group,with statistical significances(P<0.05).Conclusion rTMS combined with muscle stretching technique can improve the symptoms of myotonia,walking ability and muscle tone in PD patients,which is an ideal intervention method,worthy of clinical application.

关 键 词：帕金森病 肌强直 经颅磁刺激 肌肉牵伸技术 步行能力 肌张力 

分 类 号：R742.5[医药卫生—神经病学与精神病学]