白蛋白、血清前白蛋白、胆碱酯酶与脑卒中长期卧床患者营养状况的相关性分析  

Correlation analysis of albumin,serum prealbumin,cholinesterase and nutritional status in long-term bedridden patients with stroke

作　　者：吴彩葵 廖少琼 WU Caikui;LIAO Shaoqiong(Department of Neurology,Nanning Eighth People's Hospital,Guangxi Zhuang Autonomous Region,Nanning530001,China)

机构地区：[1]广西壮族自治区南宁市第八人民医院神经内科,广西南宁530001

出　　处：《中国当代医药》2025年第5期57-60,共4页China Modern Medicine

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(Z-A20221235)。

摘　　要：目的分析脑卒中长期卧床患者营养状况与白蛋白(ALB)、血清前白蛋白(PA)、胆碱酯酶(CHE)的相关性。方法选取2022年7月至2023年7月南宁市第八人民医院收治的72例脑卒中长期卧床患者作为研究对象,根据营养风险筛查(NRS-2002)评分结果分为有营养风险组(NRS-2002≥3分,n=42)和无营养风险组(NRS-2002<3分,n=30)。比较两组患者的ALB、PA、CHE、血红蛋白(HGB)等血清指标和体重指数(BMI)的差异,采用Pearson相关性分析不同营养状态与BMI、HGB、ALB、PA、CHE的相关性。结果有营养风险组的HGB、ALB、PA、CHE、BMI低于无营养风险组,差异有统计学意义(P<0.05);Pearson相关性分析显示,BMI(r=-0.426,P=0.038)、HGB(r=-0.361,P=0.026)、ALB(r=-0.441,P=0.042)、PA(r=-0.346,P=0.018)、CHE(r=-0.461,P=0.044)与NRS-2002评分呈负相关。结论ALB、PA、CHE检测在脑卒中长期卧床患者营养状况评估中可行性较高,可为临床医师制订合理营养干预方案提供参考。Objective To analyze the correlation between nutritional status and albumin(ALB),serum prealbumin(PA)and cholinesterase(CHE)in long-term bedridden patients with stroke.Methods A total of 72 patients with long-term bedridden stroke admitted to the Nanning Eighth People's Hospital from July 2022 to July 2023 were selected as study subjects.According to the scores of the nutrition risk screening 2022(NRS-2002),they were divided into the nutritional risk group(NRS-2002≥3 points,n=42)and the non-nutritional risk group(NRS-2002<3 points,n=30).The differences of serum indexes such as ALB,PA,CHE,hemoglobin(HGB)and body mass index(BMI)were compared between the two groups.Pearson correlation was used to analyze the correlation between different nutritional status and BMI,HGB,ALB,PA and CHE.Results The HGB,ALB,PA,CHE and BMI of the nutritional risk group were lower than those of the non-nutritional risk group,and the differences were statistically significant(P<0.05).Pearson correlation analysis showed that BMI(r=-0.426,P=0.038),HGB(r=-0.361,P=0.026),ALB(r=-0.441,P=0.042),PA(r=-0.346,P=0.018),CHE(r=-0.461,P=0.044)were negatively correlated with the score of NRS-2002.Conclusion ALB,PA and CHE can be used to evaluate the nutritional status of long-term bedridden patients with stroke,which can provide reference for clinicians to make rational nutrition intervention programs.

关 键 词：血清前白蛋白 胆碱酯酶 血红蛋白 营养风险筛查 脑卒中 长期卧床 营养状况 

分 类 号：R743.3[医药卫生—神经病学与精神病学]