阿尔茨海默病和帕金森病与肌少症的研究进展  

Research progress in Alzheimer′s disease,Parkinson′s disease and sarcopenia

作　　者：刘秋皖 张康睿 谈政 吴竹青[1] 王小强[1] 张持[1] 吴君仓[1] Liu Qiuwan;Zhang Kangrui;Tan Zheng;Wu Zhuqing;Wang Xiaoqiang;Zhang Chi;Wu Juncang(Department of Neurology,Hefei Second People′s Hospital,Hefei Hospital Affiliated to Anhui Medical University,Hefei 230011,China)

机构地区：[1]合肥市第二人民医院·安徽医科大学附属合肥医院神经内科,合肥230011

出　　处：《中华老年多器官疾病杂志》2025年第2期157-160,共4页Chinese Journal of Multiple Organ Diseases in the Elderly

基　　金：合肥市关键共性技术研发项目(GJ2022SM07)。

摘　　要：阿尔茨海默病(AD)与帕金森病(PD)是最常见的神经系统退行性疾病,与肌少症都是老年性疾病。现有研究表明,AD、PD与肌少症间密切相关,肌少症在AD与PD患者中具有较高患病率,但其发生肌少症的机制尚未阐明。本文全面综述了这两种疾病合并肌少症的流行病学特点、发病机制及防治措施,以期提高临床工作者对二者共病的认识。Alzheimer′s disease(AD)and Parkinson′s disease(PD)are the most common neurodegenerative diseases,and both of them and sarcopenia are senile disease.Existing studies show that PD,AD,and sarcopenia are closely related.Sarcopenia has a high prevalence in AD and PD patients,but the mechanism of the occurrence of sarcopenia in these patients has not been clarified.In this paper,we comprehensively reviewed the epidemiological characteristics,pathogenesis,and prevention measures of these two diseases with comorbid sarcopenia in order to improve the understanding of their comorbidity in the clinical professionals.

关 键 词：阿尔茨海默病 帕金森病 神经系统退行性疾病 肌少症 

分 类 号：R741[医药卫生—神经病学与精神病学] R592[医药卫生—临床医学]