外周输注胺碘酮致化学性静脉炎的预防研究进展  

Research progress on the prevention of chemical phlebitis induced by peripheral infusion amiodarone

作　　者：谭敏 杨波 张娜[1] TAN Min;YANG Bo;ZHANG Na(Department of Thoracic Surgery,Cancer Hospital of Chinese Academy of Medical Sciences,Beijing100021,China)

机构地区：[1]中国医学科学院肿瘤医院胸外科,北京100021

出　　处：《中国当代医药》2025年第6期193-198,共6页China Modern Medicine

摘　　要：胺碘酮是治疗心律失常的常用药物,但在应用过程中发现,胺碘酮会对外周血管产生较强刺激性,可能引发化学性静脉炎。静脉炎的发生可能对患者的治疗造成一定影响,为此,本文从药物因素、护理因素、患者因素三个方面对胺碘酮致化学性静脉炎的原因进行了分析,并对预防和护理的具体方法包括合理配置药液、保护性静脉穿刺、控制持续输注时间、增加冲封管量、静脉回血的处理、预防性药物、规范的健康教育进行了综述。此外对预防胺碘酮致化学性静脉炎的新进展进行了总结,旨在为临床医务工作者制订针对静脉注射胺碘酮致化学性静脉炎的干预措施提供依据。Amiodarone is a commonly used medication for the treatment of arrhythmias,however,during its application,it has been observed that amiodarone exerts a significant irritant effect on peripheral blood vessels,which may lead to chemical phlebitis.The occurrence of phlebitis can impact the treatment of patients.Therefore,this paper analyzes the causes of amiodarone-induced chemical phlebitis from three perspectives:drug-related factors,nursing-related factors,and patient-related factors.It also reviews specific prevention and nursing methods,including the rational preparation of the drug solution,protective venipuncture,controlling the duration of continuous infusion,increasing the flushing volume,managing venous blood reflux,local application of vasodilators,prophylactic medications,and standardized health education.Furthermore,the paper summarizes the recent advances in the prevention of amiodarone-induced chemical phlebitis,aiming to provide a basis for clinical healthcare professionals to develop targeted interventions against amiodarone-induced chemical phlebitis during intravenous administration.

关 键 词：胺碘酮 静脉炎 预防 心律失常 

分 类 号：R364.5[医药卫生—病理学]