3.0T核磁共振成像及血清黏蛋白5AC、异常糖链糖蛋白单独及联合检测对胰腺癌的诊断价值  

Diagnostic value of 3.0T nuclear magnetic resonance imaging and serum mucin 5AC,tumor abnormal protein single and combined detection in pancreatic cancer

作　　者：杨惠娅[1] 沈丽萍 陈建新[1] YANG Huiya;SHEN Liping;CHEN Jianxin(Department of Imaging,Zhangjiagang First People’s Hospital,Zhangjiagang 215600,Jiangsu,China)

机构地区：[1]张家港市第一人民医院影像科,江苏张家港215600

出　　处：《癌症进展》2025年第2期167-170,共4页Oncology Progress

基　　金：江苏省中医药科技发展计划项目(MS2021064)。

摘　　要：目的探讨3.0T核磁共振成像(NMRI)及血清黏蛋白5AC(MUC5AC)、异常糖链糖蛋白(TAP)单独及联合检测对胰腺癌的诊断价值。方法选取87例疑似胰腺癌患者,接受NMRI检查及血清MUC5AC、TAP水平检测。以病理检查结果为金标准,评估3.0T NMRI及血清MUC5AC、TAP单独及联合检测对胰腺癌的诊断价值。结果病理检查结果显示,87例疑似胰腺癌患者中,胰腺癌37例,胰腺炎50例。NMRI及血清MUC5AC、TAP联合检测诊断胰腺癌的灵敏度为94.59%,特异度为90.00%,准确度为91.95%,阳性预测值为87.50%,阴性预测值为95.74%,均高于各指标单独检测。结论3.0T NMRI及血清MUC5AC、TAP联合检测诊断胰腺癌的价值较高,或可提高临床胰腺癌的早期检出率。Objective To analyze the diagnostic value of 3.0T nuclear magnetic resonance imaging(NMRI)and serum mucin 5AC(MUC5AC),tumor abnormal protein(TAP)single and combined detection in pancreatic cancer.Method A total of 87 patients with suspected pancreatic cancer were selected to receive NMRI examination and serum MUC5AC,TAP levels detection.The pathological examination results as the gold standard,the diagnostic value of 3.0T NMRI and serum MUC5AC,TAP single and combined detection in pancreatic cancer were evaluated.Result Pathological examination showed that among 87 patients with suspected pancreatic cancer,37 cases were pancreatic cancer and 50 cases were pancreatitis.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of NMRI,serum MUC5AC and TAP combined detection in diagnosis of pancreatic cancer were 94.59%,90.00%,91.95%,87.50%,and 95.74%,respectively,which were higher than those of each indicator single detection.Conclusion The 3.0T NMRI,serum MUC5AC and TAP combined detection has high value in the diagnosis of pancreatic cancer,maybe can improve the early detection rate of clinical pancreatic cancer.

关 键 词：胰腺癌 核磁共振成像 黏蛋白5AC 异常糖链糖蛋白 诊断 

分 类 号：R735.9[医药卫生—肿瘤]