胸腔镜下不同肺切除术对非小细胞肺癌患者术后早期功能恢复的影响  

Effect of different types of thoracoscopic pulmonary resection on early functional recovery in patients with non-small cell lung cancer

作　　者：张印[1] 庞彬[1] 曹睿 ZHANG Yin;PANG Bin;CAO Rui(Ward 2,Department of Thoracic Surgery,Nanyang Second General Hospital,Nanyang 473000,He’nan,China)

机构地区：[1]南阳市第二人民医院胸外科二病区,河南南阳473000

出　　处：《癌症进展》2025年第2期222-224,244,共4页Oncology Progress

摘　　要：目的探讨胸腔镜下不同肺切除术对非小细胞肺癌(NSCLC)患者术后早期功能恢复的影响。方法将86例NSCLC患者根据手术方式的不同分为A组42例和B组44例,A组患者采取胸腔镜下肺段切除术,B组患者采取胸腔镜下肺叶切除术。比较两组患者临床指标、肺功能指标[第1秒用力呼气容积(FEV_(1))、用力肺活量(FVC)及最大自主通气量(MVV)]及并发症发生情况。结果A组患者手术时间明显长于B组,引流量及出血量均明显多于B组,肺段切除数明显少于B组,差异均有统计学意义(P﹤0.01)。术后,两组患者FEV_(1)、FVC、MVV水平均较术前升高,且A组患者FEV_(1)、FVC、MVV水平均高于B组,差异均有统计学意义(P﹤0.05)。两组患者并发症总发生率比较,差异无统计学意义(P﹥0.05)。结论NSCLC患者采取胸腔镜下肺段切除术、肺叶切除术均可获得满意的效果,其中肺叶切除术可减轻患者的创伤,而肺段切除术可减轻对患者肺功能的影响。Objective To investigate the effect of different types of thoracoscopic pulmonary resection on early functional recovery in patients with non-small cell lung cancer(NSCLC).Method A total of 86 patients with NSCLC were divided into group A(42 cases)and Group B(44 cases)according to different surgical methods.Patients in group A underwent thoracoscopic pulmonary segmental resection,and patients in group B underwent thoracoscopic lobectomy.The clinical indicators,pulmonary function indicators[forced expiratory volume in one second(FEV_(1)),forced vital capacity(FVC)and maximal voluntary ventilation(MVV)]and the incidence of complications were compared between the two groups.Result The operation time in group A was significantly longer than that in group B,the drainage volume and blood loss were significantly more than those in group B,and the number of lung segments removed was significantly less than that in group B,the differences were statistically significant(P<0.01).After surgery,the levels of FEV_(1),FVC and MVV in two groups were higher than those before surgery,and the levels of FEV_(1),FVC and MVV in group A were higher than those in group B,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).Conclusion Both thoracoscopic pulmonary segmental resection and pulmonary lobectomy can achieve satisfactory results in patients with NSCLC.Thoracoscopic pulmonary lobectomy can reduce the trauma of patients,while thoracoscopic pulmonary segmental resection can reduce the impact on lung function of patients.

关 键 词：非小细胞肺癌 胸腔镜 肺段切除术 肺叶切除术 肺功能 

分 类 号：R734.2[医药卫生—肿瘤]