免疫调节剂治疗急性坏死性脑病的研究进展  

Immunomodulator treatment for acute necrotizing encephalopathy

作　　者：牛杰朝 王怀立[1] Niu Jiechao;Wang Huaili(Pediatric Intensive Care Unit,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院儿童重症监护室,450052

出　　处：《中国小儿急救医学》2025年第2期94-97,共4页Chinese Pediatric Emergency Medicine

摘　　要：急性坏死性脑病(ANE)是一种罕见的急性中枢神经系统破坏性病变,多见于4岁以下儿童,急性起病,迅速进展,病死率高,幸存者常遗留严重的神经系统后遗症。近年来,免疫调节剂的应用为ANE的治疗带来了新的希望。本文对免疫调节剂在ANE治疗中的应用研究进行分析,为临床应用提供更好的依据。Acute necrotizing encephalopathy(ANE)is a rare,acute,destructive central nervous system disorder,primarily affecting children.It has an acute onset,rapid progression,a high mortality rate,and survivors often suffer from severe neurological sequelae.In recent years,the use of immunomodulatory agents has brought new hope for the treatment of ANE.This review analyzed the application of immunomodulatory agents in the treatment of ANE,providing a basis for better clinical guidance.

关 键 词：急性坏死性脑病 神经系统疾病 免疫调节剂 预后 

分 类 号：R74[医药卫生—神经病学与精神病学]