甲状腺结节与脂肪肝的相关性及可能机制  

Correlation and possible mechanisms between thyroid nodules and fatty liver disease

作　　者：裴蕾蕾 李春睿 吴燕 曹淑洁 Pei Leilei;Li Chunrui;Wu Yan;Cao Shujie(Department of Endocrinology,Sunshine Union Hospital,Weifang 261061,China)

机构地区：[1]阳光融和医院内分泌科,潍坊261061

出　　处：《国际内分泌代谢杂志》2025年第1期35-38,共4页International Journal of Endocrinology and Metabolism

摘　　要：脂肪肝和甲状腺结节均为临床常见慢性疾病,发病率日趋增加,脂肪肝若不及时控制可逐渐发展为肝硬化,甚至肝癌,甲状腺结节亦有恶变风险,故均需尽早诊断。但在临床中很难对所有人群进行肝脏彩超及甲状腺超声检查。新近研究显示,两种疾病之间存在相关关系,且可能互相影响。这一发现可为确定疾病的筛查对象提供依据。部分研究显示,代谢紊乱、胰岛素抵抗、瘦素、雌激素可能在其中扮演了部分角色,但由于此类研究尚处于起步阶段,其中的具体机制目前尚不明确,亟需进一步探讨。Fatty liver and thyroid nodules are common chronic diseases in clinics,and the incidence rate is increasing day by day.If fatty liver is not controlled in time,it can gradually develop into cirrhosis,even liver cancer.Thyroid nodules also have the risk of canceration,so early diagnosis is needed.However,it is difficult to perform liver ultrasound and thyroid ultrasound examinations on all populations in clinical practice.Recent studies have shown that there is a correlation between the two diseases and they are risk factors for each other.This discovery can provide a basis for determining the screening targets for diseases.Some studies have shown that metabolic disorders,insulin resistance,leptin,and estrogen may play some roles,but due to this type of research being in its early stages,the specific mechanisms involved are currently unclear and require further exploration.

关 键 词：甲状腺结节 脂肪肝 代谢综合征 胰岛素抵抗 雌激素 

分 类 号：R73[医药卫生—肿瘤]