儿童胰腺肿瘤手术切除单中心经验总结  

Single center experience in surgical resection of pediatric pancreatic tumors

作　　者：沈刚 翟允鹏[1] 赵华善 许洪修 郭锐[1] 黄赛 张士松[1] Shen Gang;Zhai Yunpeng;Zhao Huashan;Xu Hongxiu;Guo Rui;Huang Sai;Zhang Shisong(Department of Thoracic and Oncology Surgery,Children's Hospital Affiliated to Shandong University(Jinan Children's Hospital),Jinan 250022,China)

机构地区：[1]山东大学附属儿童医院(济南市儿童医院)胸外肿瘤外科,济南250022

出　　处：《中华肝胆外科杂志》2025年第2期111-115,共5页Chinese Journal of Hepatobiliary Surgery

基　　金：济南市卫生健康委员会科技计划(2023-1-53);山东大学附属儿童医院2023年高层次科研计划(SDFE-GCC2023005)。

摘　　要：目的总结儿童胰腺肿瘤的手术处理策略。方法回顾性分析2018年1月至2024年4月于山东大学附属儿童医院行手术治疗的17例胰腺肿瘤患儿临床资料,其中男性6例,女性11例,年龄范围1月~13岁,中位年龄10岁2个月。分析肿瘤长径、肿瘤位置、手术方式、术后病理等资料。定期打电话及门诊复查随访所有患儿预后情况。结果17例患儿肿瘤长径为(7.3±2.2)cm,肿瘤位于胰头10例,位于胰体尾7例,伴肝转移1例,伴左侧肾上腺浸润1例。17例患儿中的10例胰头肿瘤,单纯胰腺肿瘤切除术6例,腹腔镜胰腺肿瘤切除术1例,胰头切除+胰腺空肠Roux-en-Y吻合术3例;7例胰体尾肿瘤中,行胰体尾切除术3例,腹腔镜胰体尾部切除术1例,肿瘤切除术1例,胰体尾切除+脾切除+肝转移瘤切除术1例,胰体尾部切除+左侧肾上腺切除+脾切除术1例。术后病理显示,胰腺实性假乳头状瘤13例,胰母细胞瘤3例,胰腺囊肿1例。随访时间2~71个月,中位数36个月,患者均生存良好。结论胰腺实性假乳头状瘤是儿童胰腺肿瘤较常见的类型,首选手术切除,术后预后良好。Objective To summarize the surgical management strategy for pediatric pancreatic tumors.Methods Clinical data of 17 children with pancreatic tumors who underwent surgical treatment in Children's Hospital Affiliated to Shandong University from January 2018 to April 2024 were retrospectively analyzed,including 6 males and 11 females,ranging in age from 1 month to 13 years,with a median age of 10 years and 2 months.The data of tumor length and diameter,tumor location,surgical method and postope-rative pathology were analyzed.The prognostic data of all children were followed up by regular telephone and outpatient follow-up.Results In 17 cases,the tumor diameter was(7.3±2.2)cm,10 cases were located in the head of the pancreas,7 cases were located in the tail of the pancreatic body,1 case was accompanied by liver metastasis,and 1 case was accompanied by left adrenal invasion.Among these cases,10 cases had pancreatic head tumor,6 cases had simple pancreatic tumor resection,1 case had laparoscopic pancreatic tumor resection,and 3 cases had pancreatic head resection plus pancreato-jejunal Roux-en-Y anastomosis.Among the 7 cases of pancreatic body and tail tumors,3 cases underwent pancreatic body and tail resection,1 case underwent laparoscopic pancreatic body and tail resection,1 case underwent tumor resection,1 case underwent pancreatic body and tail resection plus splenectomy plus hepatic metastasis resection,1 case underwent pancreatic body and tail resection plus left adrenal resection plus splenectomy.Postoperative pathology showed that there were 13 cases of solid pseudopapilloma,3 cases of pancreatic blastoma,and 1 case of pancreatic cyst.The median follow-up time was 36 months(2-71 months).All patients survived well.Conclusion Solid pseudopapillary of the pancreas is the most common type of pancreatic tumor in children,with surgical resection being the first choice of of treatment,offering a favorable prognosis postope-ratively.

关 键 词：胰腺肿瘤 外科手术治疗 儿童 

分 类 号：R73[医药卫生—肿瘤]