口腔癌游离皮瓣修复患者术后生存质量影响因素调查研究  

The Investigation on the Influencing Factors of Postoperative Quality of Life in Patients with Oral Cancer Repaired by Free Flap

作　　者：郑晓姣 顾婷立 赵苏峰 ZHENG Xiaojiao;GU Tingli;ZHAO Sufeng(Department of Oral and Maxillofacial Surgery,Affiliated Stomatological Hospital of Nanjing University School of Medicine,Nanjing Stomatological Hospital,Nanjing,Jiangsu 210000,China)

机构地区：[1]南京大学医学院附属口腔医院、南京市口腔医院口腔颌面外科,江苏南京210000

出　　处：《转化医学杂志》2024年第11期1936-1939,共4页Translational Medicine Journal

基　　金：南京市卫生科技发展专项资金项目计划(ZKX21056)。

摘　　要：目的探讨口腔癌游离皮瓣修复术后患者的生存质量及其影响因素。方法选择南京市口腔医院口腔癌游离皮瓣修复患者180例,调查患者术后生存质量,收集患者各项资料,比较不同基线资料患者术后生存质量差异,采用多元线性回归分析探究影响患者术后生存质量的因素。结果口腔癌游离皮瓣修复患者术后3个月疼痛、情绪、肩部功能、外形、咀嚼、活动方面生存质量评分高于术前,患者术后3个月总生存质量评分高于术前(P<0.05);单因素与多元线性回归分析结果显示年龄、文化水平、临床分期、颈部清扫术、缺损范围、术后化疗、术后放疗为患者生存质量影响因素(P<0.05),婚姻状态不是患者生存质量影响因素(P>0.05)。结论口腔癌游离皮瓣修复患者术后生存质量较术前改善,年龄、文化水平、临床分期、颈部清扫术、缺损范围等因素与患者术后生存质量相关,可以以此为基础制定针对性干预措施以改善患者生存质量。Objective To investigate the quality of life in patients after oral cancer free flap repair and its influencing factors.Methods A total of 180 patients who underwent oral cancer free flap repair in Nanjing Stomatological Hospital were included.The postoperative quality of life was investigated,and various data were collected.The difference of postoperative quality of life for patients with different baseline data was compared,and the influencing factors of postoperative quality of life were analyzed by multiple linear regression.Results Quality of life(QOL)scores in pain,emotion,shoulder function,shape,mastication,and activity were higher 3 months after surgery than before surgery,and the total QOL score was higher(P<0.05);Univariate and multiple linear regression analysis showed that age,education level,clinical stage,neck dissection,defect scope,postoperative chemotherapy,and postoperative radiotherapy were the influencing factors of patients'quality of life(P<0.05),while marital status was not(P>0.05).Conclusion Quality of life after oral cancer free flap repair is improved compared with that before surgery.Age,education level,clinical stage,neck dissection,defect scope,and other factors are related to the postoperative quality of life,so targeted intervention measures can be developed on this basis to improve the quality of life of patients.

关 键 词：口腔癌 游离皮瓣修复 生存质量 影响因素 

分 类 号：R739.8[医药卫生—肿瘤]