pT_(2-3)N_(0)M_(0)期胸段食管鳞状细胞癌治疗策略及预后影响因素研究进展  

Research progress in treatment strategies and prognostic factors for stage pT_(2-3)N_(0)M_(0)thoracic esophageal squamous cell carcinoma

作　　者：余洋 唐仕敏[2] 杨露 李娜 Yu Yang;Tang Shimin;Yang Lu;Li Na(Department of Clinical Medicine,North Sichuan Medical College,Nanchong 637000,China;Department of Cancer Center,Suining Central Hospital of Sichuan Province,Suining 629000,China)

机构地区：[1]川北医学院临床医学系,南充637000 [2]四川省遂宁市中心医院肿瘤中心,遂宁629000

出　　处：《国际肿瘤学杂志》2025年第1期43-47,共5页Journal of International Oncology

基　　金：四川省重点研发项目(2023YFS0488);遂宁市中心医院科研课题(2022ypj03)。

摘　　要：pT_(2-3)N_(0)M_(0)期胸段食管鳞状细胞癌患者虽然分期较早,但术后局部复发及远处转移率较高,导致此类患者5年生存率较低,并且目前此类患者的新辅助治疗仍处在研究阶段,术后是否予以辅助放化疗仍存在争议。此外,pT_(2-3)N_(0)M_(0)期胸段食管鳞状细胞癌患者的预后影响因素尚未明确,复发与转移的原因尚不清楚。因此,明确治疗策略及探索预后影响因素对提高此类患者的生存率有重要意义,有望为pT_(2-3)N_(0)M_(0)期胸段食管鳞状细胞癌患者改善预后、提高生存率提供新方向。Although patients with stage pT_(2-3)N_(0)M_(0)thoracic esophageal squamous cell carcinoma are staged earlier,their postoperative local recurrence and distant metastasis rates are higher,resulting in a low five-year survival rate of such patients.The current neoadjuvant treatment for such patients is still in the research stage,and whether to give adjuvant radiotherapy and chemotherapy after surgery is still controversial.In addition,the prognostic factors of patients with pT_(2-3)N_(0)M_(0)thoracic esophageal squamous cell carcinoma have not yet been clarified,and the causes of recurrence and metastasis are not yet clear.Therefore,it is of great significance to clarify treatment strategies and explore the impact of prognostic factors on improving the survival rate of such patients,which is expected to provide new directions for improving the prognosis and survival rate of patients with pT_(2-3)N_(0)M_(0)thoracic esophageal squamous cell carcinoma.

关 键 词：食道鳞癌 肿瘤治疗方案 预后 

分 类 号：R73[医药卫生—肿瘤]