颅内血肿微创抽吸引流术联合尿激酶、吡拉西坦治疗自发性基底节区脑出血的研究  

Study on Minimally Invasive Aspiration and Drainage of Intracranial Hematoma Combined with Urokinase and Piracetam for the Treatment of Spontaneous Basal Ganglia Intracerebral Hemorrhage

作　　者：赖鹏飞 黄国骥 罗曙辉 LAI Pengfei;HUANG Guoji;LUO Shuhui(Yudu County People’s Hospital,Yudu342300,Jiangxi,China)

机构地区：[1]于都县人民医院,江西于都342300

出　　处：《现代诊断与治疗》2024年第22期3328-3330,共3页Modern Diagnosis and Treatment

基　　金：赣州市科技计划项目(项目编号:GZ2023ZSF795)。

摘　　要：目的研究颅内血肿微创抽吸引流术联合尿激酶、吡拉西坦治疗基底节区自发性脑出血的疗效及对患者神经功能和并发症的影响。方法选取2022年1月至2024年4月我院收治的60例基底节区自发性脑出血患者为研究对象,按随机数字表法分为对照组和观察组各30例。对照组给予颅内血肿微创抽吸引流术治疗,观察组在对照组基础上联合尿激酶、吡拉西坦治疗。比较两组临床疗效、神经功能缺损程度[美国国立卫生研究院卒中量表(NIHSS)评分]及并发症发生情况。结果观察组治疗总有效率高于对照组(P<0.05);观察组治疗后NIHSS评分低于对照组(P<0.05);观察组并发症发生率低于对照组(P<0.05)。结论颅内血肿微创抽吸引流术联合尿激酶、吡拉西坦治疗基底节区自发性脑出血效果显著,可提高治疗总有效率,减轻患者神经功能缺损程度,且术后并发症发生率低。Objectives To investigate the efficacy of minimally invasive aspiration and drainage of intracranial hematoma combined with urokinase and piracetam in the treatment of spontaneous intracerebral hemorrhage in the basal ganglia,as well as its impact on neurological function and complications in patients.Methods A total of 60 patients with spontaneous intracerebral hemorrhage in the basal ganglia admitted to our hospital from January 2022 to April 2024 were selected as the research objects.According to the random number table method,they were randomly divided into control group and observation group,with 30 patients in each group.The control group was treated with minimally invasive aspiration and drainage of intracranial hematoma,while the observation group received urokinase and piracetam on the basis of the control group.The clinical efficacy,degree of neurological deficit[National Institutes of Health Stroke Scale(NIHSS)score]and complications were compared between the two groups.Results The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the NIHSS score of the observation group was significantly lower than that in the control group(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).Conclusions Minimally invasive aspiration and drainage of intracranial hematoma combined with urokinase and piracetam is effective in the treatment of spontaneous intracerebral hemorrhage in the basal ganglia,which can improve the total effective rate of treatment,reduce the degree of neurological deficit in patients,and has a low incidence of postoperative complications.

关 键 词：自发性基底节区脑出血 颅内血肿微创抽吸引流术 尿激酶 吡拉西坦 

分 类 号：R743.3[医药卫生—神经病学与精神病学]