儿童腹部散发性伯基特 淋巴瘤临床表现及CT 特征分析  

To Analyze the Clinical Manifestations and CT Features of Abdominal Sporadic Burkitt Lymphoma in Children

作　　者：李钱程 王伟 张龚巍[3] 李成龙 辛涛 代秀红 李世宪 吴宝玉 程祖盛 LI Qian-cheng;WANG Wei;ZHANG Gong-wei;LI Cheng-long;XIN Tao;DAI Xiu-hong;LI Shi-xian;WU Bao-yu;CHENG Zu-sheng(Department of Radiology,Xuzhou Children's Hospital,Xuzhou 221000,Jiangsu Province,China;Department of Neonatology,Xuzhou Children's Hospital,Xuzhou 221000,Jiangsu Province,China;Department of Radiology,Shenzhen Children's Hospital,Shenzhen 518003,Guangdong Province,China;Department of General Surgery,Xuzhou Children's Hospital,Xuzhou 221000,Jiangsu Province,China;Department of Pathology,Xuzhou Children's Hospital,Xuzhou 221000,Jiangsu Province,China;Department of Radiology,Shaoxing 7th People's Hospital,Shaoxing 312000,Zhejiang Province,China)

机构地区：[1]徐州市儿童医院放射科,江苏徐州221000 [2]徐州市儿童医院新生儿科,江苏徐州221000 [3]深圳市儿童医院放射科,广东深圳518003 [4]徐州市儿童医院普外科,江苏徐州221000 [5]徐州市儿童医院病理科,江苏徐州221000 [6]绍兴市第七人民医院放射科,浙江绍兴312000

出　　处：《中国CT和MRI杂志》2025年第3期161-164,共4页Chinese Journal of CT and MRI

基　　金：江苏省徐州市卫生健康委医学科技创新项目(XWKYHT20230018)。

摘　　要：目的探讨儿童腹部散发性伯基特淋巴瘤(BL)临床及CT表现特征,以期增强儿童腹部BL影像学的认识,提高临床诊断准确率。方法以2015年1月至2024年5月徐州市儿童医院经手术或(和)穿刺活检病理证实的儿童腹部18例BL患儿作为研究对象,回顾性分析患儿的一般临床特点及CT影像学特征。结果(1)18例儿童腹部散发性BL病例,发病年龄中位数6.2岁,男性占94.4%(17/18),临床表现以腹部包块和腹痛为主,儿童腹部散发性BL并发肠套叠发生率较高,占50.0%(9/18);(2)儿童腹部散发性BL病灶部位以胃肠道回盲部及小肠为主,占比61.1%(11/18);CT平扫病灶表现主要为等低密度软组织包块或肠壁增厚,CT增强扫描病灶轻度强化8例,中度强化8例,明显强化2例;部分病例可见肠管扩张、病灶跳跃分布特点,肠系膜周围BL病灶可见“三明治征”;其中仅1例继发性肝、胰及肾浸润。结论儿童腹部散发性BL的临床及CT表现具有一定特征性,对于男性患儿、腹部包块/腹痛或反复发生肠套叠的患儿应及时完善腹部影像学检查,为临床进一步诊治提供依据。Objective To explore the clinical and CT manifestation characteristics of sporadic Burkitt lymphoma(BL)in children,aiming to enhance the understanding of imaging findings in pediatric abdominal BL and improve the accuracy of clinical diagnoses.Methods This study involved a retrospective analysis of 18 pediatric patients with abdominal BL who underwent surgery and/or biopsy confirmation at the Xuzhou Children's Hospital from January 2015 to May 2024.General clinical characteristics and CT imaging features of the patients were analyzed.Results(1)Among the 18 cases of pediatric sporadic abdominal BL,the median age of onset was 6.2 years,with males representing 94.4%(17/18).The main clinical manifestations were abdominal masses and abdominal pain,with a high incidence of intussusception complicating the condition,accounting for 50.0%(9/18).(2)The primary lesion sites of pediatric abdominal sporadic BL were mainly in the gastrointestinal tract,particularly the ileocecal region and small intestine,accounting for 61.1%(11/18).The CT plain scan showed lesions predominantly as iso-hypodense soft tissue masses or thickened bowel walls.On CT enhancement scans,mild enhancement was observed in 8 cases,moderate enhancement in 8 cases,and marked enhancement in 2 cases.Some cases showed intestinal dilation and a jumping distribution of lesions,with the"sandwich sign"evident around mesenteric BL lesions;only one case demonstrated secondary infiltration of the liver,pancreas,and kidneys.Conclusion The clinical symptoms and CT manifestations of pediatric sporadic BL exhibit certain characteristic features.For male patients presenting with abdominal masses/pain or recurrent intussusception,prompt abdominal imaging should be performed to provide a basis for further clinical diagnosis and treatment.

关 键 词：儿童 伯基特淋巴瘤 临床指标 体层摄影术 X线计算机 

分 类 号：R733.4[医药卫生—肿瘤]