Cellular pathophysiology of Duchenne muscular dystrophy: insights from a novel rhesus macaque model  

作　　者：Alessandra Moretti Christian Kupatt Eckhard Wolf 

机构地区：[1]Medical Department I,Cardiology,Angiology,Pneumology,Klinikum rechts der Isar,Technical University of Munich,School of Medicine and Health,81675,Munich,Germany [2]DZHK(German Center of Cardiovascular Research),Munich Heart Alliance,80336,Munich,Germany [3]Gene Center and Center for Innovative Medical Models(CiMM),LMU Munich,81377,Munich,Germany [4]Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer(ICONLMU),LMU Munich,81377,Munich,Germany

出　　处：《Signal Transduction and Targeted Therapy》2025年第1期5-6,共2页信号转导与靶向治疗(英文)

基　　金：supported by the ForTra gGmbH für Forschungstransfer der EKFS(2018_T20;2022_EKSE.41);A.M.and C.K.by the European Research Council(ERC,101141820 and 101021043);E.W.by the Leducq Foundation(Network 23CVD01).

摘　　要：In a recent study published in Cell,Ren and colleagues1 present a new rhesus macaque(Macaca mulatta)model for Duchenne muscular dystrophy(DMD)and a comprehensive single-cell analysis of skeletal muscle,providing detailed insights into the cellular pathophysiology.

关 键 词：DYSTROPHY DUCHENNE MUSCULAR 

分 类 号：R74[医药卫生—神经病学与精神病学]