轴率比诊断不同角膜曲率儿童青少年近视的准确性评估  

The Accuracy of Axial Ratio in Evaluating Myopia in Adolescents with Different Corneal Curvature

作　　者：仝欢 陈巍[1] 刘新丽 冯晶晶[1] 王立华 邢杉杉 浦佳宁 Huan Tong;Wei Chen;Xinli Liu;Jingjing Feng;Lihua Wang;Shanshan Xing;Jianing Pu(Department of Ophthalmology,Haidian Maternal and Child Care Health Hospital,Beijing 100080,China)

机构地区：[1]北京市海淀区妇幼保健院眼科,北京100080

出　　处：《中华眼视光学与视觉科学杂志》2025年第1期62-66,共5页Chinese Journal Of Optometry Ophthalmology And Visual Science

摘　　要：目的:探讨眼轴(AL)与角膜曲率半径(CR)的比值(轴率比,AL/CR)在不同角膜曲率的儿童青少年中诊断近视的准确性及诊断界值。方法:横断面研究。随机选取2022年6月至2024年6月在北京市海淀区妇幼保健院眼科就诊的3~15岁儿童青少年3424例,对所有入组患者进行睫状肌麻痹后验光获得等效球镜度(SE),检查记录AL、平均CR,并计算AL/CR值。以SE≤-0.50 D为近视诊断标准,利用受试者工作特征曲线(ROC)计算AL/CR在不同角膜曲率组的近视诊断界值。AL和AL/CR组间比较采用单因素方差分析,SE组间比较采用秩和检验。结果:根据年龄分为3~7岁组、8~11岁组和12~15岁组3组,再根据CR将各年龄组分为高曲率组(CR<7.51)、中曲率组(7.51≤CR≤7.99)、低曲率组(CR>7.99)。整体的高、中、低曲率组AL和AL/CR比较差异均有统计学意义(F=256.32、59.39,均P<0.001);同一曲率不同年龄组的AL/CR和SE比较差异均有统计学意义(均P<0.05)。通过ROC曲线得出不同年龄组及不同曲率组AL/CR诊断近视的界值:3~7岁组高、中、低曲率组分别为3.00、2.95、2.88;8~11岁组高、中、低曲率组分别为3.09、3.04、2.94;12~15岁组高、中、低曲率组分别为3.16、3.06、3.07。ROC曲线下面积均为90%以上。结论:AL/CR可用于不同曲率儿童青少年近视的定性诊断,诊断界值随年龄的增加有增高的趋势,同年龄组中诊断界值随曲率的降低而降低。Objective:To investigate the accuracy and diagnostic threshold of the ratio of axial length(AL)to corneal curvature radius(CR)in diagnosing myopia among children and adolescents with varying corneal curvatures.Methods:This was a cross sectional study.A total of 3424 children and adolescents aged 3 to 15 years who were treated in the Department of Ophthalmology,Haidian Maternal and Child Care Health Hospital from June 2022 to June 2024 were randomly selected in this study.The equivalent spherical degree(SE)was obtained by optometry after ciliary muscle paralysis,AL and mean CR were also recorded,and AL/CR values were calculated.With SE≤-0.50 D as the diagnostic criterion for myopia,the diagnostic threshold of AL/CR in different corneal curvature groups was calculated by receiver operating characteristic(ROC)curve.One-way ANOVA was used for comparison of AL and AL/CR groups,and rank-sum test was used for comparison between SE groups.Results:Participants in this study were divided into 3 groups according to age:3-7 years old,8-11 years old and 12-15 years old.According to CR,they were divided into high curvature group(CR<7.51),medium curvature group(7.51≤CR≤7.99),and low curvature group(CR>7.99).AL and AL/CR in the whole high,medium and low curvature groups were significantly different,respectively(F=256.32,59.39,both P<0.001).There were significant differences in AL/CR and SE in different age groups(all P<0.05).The cut-off values of AL/CR in diagnosis of myopia in different age groups and different curvature groups were obtained by ROC curve:3.00,2.95,and 2.88,respectively,in high,medium,and low curvature groups in 3-7 years old group.The high,medium,and low curvature groups in 8 to 11 years old were 3.09,3.04,and 2.94,respectively.The high,medium,and low curvature groups in the 12-15 years old group were 3.16,3.06,and 3.07,respectively.The area under ROC curve was more than 90%.Conclusions:AL/CR can be used for the qualitative evaluation of myopia in children and adolescents with different corneal curvatures

关 键 词：眼轴 角膜曲率半径 轴率比 近视 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]