从豁闭通腑法论治晚期肝癌  

Discussion on the treatment of advanced liver cancer from the method of opening the closure and unblocking fu-organs

作　　者：葛媛莎 许博文 李杰[2] 王贺平 曹璐畅 GE Yuansha;XU Bowen;LI Jie;WANG Heping;CAO Luchang(Beijing University of Chinese Medicine,Beijing 100029,China;Oncology Department,Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)

机构地区：[1]北京中医药大学,北京100029 [2]中国中医科学院广安门医院肿瘤科,北京100053

出　　处：《天津中医药》2025年第3期306-310,共5页Tianjin Journal of Traditional Chinese Medicine

基　　金：北京市科技计划课题(Z221100003522021)。

摘　　要：肝癌进展迅速、病死率高,探索其有效治疗方法为临床重要课题。针对晚期肝癌临床病机特征,作者将其聚焦于恶性肿瘤五期演变“闭”之阶段,从胆腑、胃肠腑、三焦腑及瘀血闭阻角度阐明其病机源流,并从疏肝利胆治黄闭、调胃畅肠治肠脑闭、宣主三焦治水闭、益气活血治瘀闭等角度以豁闭通腑法论治晚期肝癌,拓展了“豁闭清源”治法的内涵。With the rapid progress and high mortality,it is an important clinical topic to explore the effective treatment of liver cancer.According to the clinical pathogenesis characteristics of advanced liver cancer,our research group focused on the“closure”phase of“five-phase evolution”of malignant tumor.Besides,we clarified its pathogenesis from the point of view of gallbladder,gastrointestinal,Sanjiao and blood stasis.And we discussed the“opening the closure and unblocking fu-organs”treatment of advanced liver cancer from the perspectives of soothing the liver and gallbladder to cure yellow closure,regulating stomach and intestine to cure intestinal cerebral atresia,promoting Sanjiao to cure water closure,and replenishing qi and activating blood circulation to cure blood stasis closure,which expanded the connotation of the treatment of“opening the closure and clearing the source”.

关 键 词：晚期肝癌 五期演变 闭 豁闭通腑 豁闭清源 

分 类 号：R735.7[医药卫生—肿瘤]