Maternal supplementation with konjac glucomannan and κ-carrageenan promotes sow performance and benefits the gut barrier in offspring  

作　　者：Feng Gao Yongqing Du Haiyang Liu Hongwei Ding Wentao Zhang Zhongyu Li Baoming Shi 

机构地区：[1]College of Animal Science and Technology,Northeast Agricultural University,Harbin 150030,Heilongjiang Province,China

出　　处：《Animal Nutrition》2024年第4期272-286,共15页动物营养(英文版)

基　　金：supported by the Major Program of Heilongjiang Province of China(2021ZX12B08).

摘　　要：This research aims to investigate the effects of dietary konjac glucomannan and κ-carrageenan(SF) on sow performance and suckling piglet gut barrier. Thirty-four sows in late gestation(parity 2-5) were selected at random and grouped into two treatments. The control group(Con group;n = 17) was fed the basal diet;the SF group was fed the same diet supplemented with 0.25% konjac glucomannan + 0.25% κ-carrageenan(SF group;n = 17). The results showed that sows fed the SF diet had a higher feed intake during lactation than the Con group(P < 0.05), and the levels of neuropeptide tyrosine(NPY)(P = 0.006)and acetylcholine enzyme(AChE)(P < 0.05) significantly increased. The fecal microbial analysis indicated that the SF diet had a higher abundance of Subdoligranulum, Holdemanella, and Succinivibrio at the genus level, and the acetate level was significantly increased(P < 0.05). Moreover, SF lowered the level of interleukin-6(IL-6) in milk(P < 0.05). Regarding suckling piglets, maternal supplementation with SF reduced jejunal IL-6 protein levels in suckling piglets(P < 0.05). In the colon of the piglet, the SF group up-regulated protein levels of occludin(P < 0.05), and the nuclear factor erythroid 2-related factor 2(Nrf2)(0.05 ≤ P < 0.10), and claudin 4(CLDN4)(0.05 ≤ P < 0.10) protein levels tended to be up-regulated.Consequently, supplementation of SF in sow diets positively affects lactation feed intake and maternal microflora. Furthermore, the maternal effect improves the jejunum and colon barriers of suckling piglets.

关 键 词：Konjac glucomannan KAPPA-CARRAGEENAN SOW Suckling piglet Gut barrier 

分 类 号：O63[理学—高分子化学]