基于生物节律视角的癫痫临床诊断策略  

Clinical diagnosis strategy of epilepsy based on biorhythm perspective

作　　者：汪亚男 伍芷君 WANG Yanan;WU Zhijun(Department of Neurosurgery,the Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou 510100,China)

机构地区：[1]广州医科大学附属脑科医院神经外科,广州510100

出　　处：《癫痫杂志》2025年第2期149-157,共9页Journal of Epilepsy

摘　　要：癫痫是一种常见的神经系统疾病,以大脑神经元异常放电引起反复发作的短暂、发作性中枢神经系统功能紊乱为特征。癫痫的诊断需要结合临床表现、脑电图、影像学检查等,临床表现复杂多变,脑电图异常是诊断癫痫的重要依据,但也有部分患者在脑电图上显示正常。此外,目前在临床上仍有较多患者因不典型癫痫症状而被漏诊。随着脑电图技术和多模态成像技术的不断发展,基于生物节律调控机制的癫痫诊断策略逐渐被提出,本文就基于生物节律调控机制在癫痫的诊断策略相关研究作一综述,以期对癫痫患者的临床诊疗提供更有效的帮助。Epilepsy is a prevalent neurological disorder characterized by recurrent,transient episodes of central nervous system dysfunction resulting from abnormal neuronal discharges in the brain.Diagnosis of epilepsy integrates clinical manifestations,electroencephalogram(EEG)findings,and imaging studies.Clinical presentations are diverse and variable,with abnormal EEG serving as a critical diagnostic indicator;however,some patients exhibit normal EEG results.Moreover,there are still many patients who were underdiagnosed because of atypical epilepsy symptoms.With advancements in EEG and multimodal imaging technologies,diagnostic strategies based on biorhythm theory have emerged.This paper reviewed the diagnostic approaches for epilepsy grounded in biorhythm theory,in order to provide more effective support for the clinical management of epilepsy.

关 键 词：生物节律 癫痫 昼夜节律 脑电图 时间药理学 

分 类 号：R74[医药卫生—神经病学与精神病学]